Sex differences in the association between neck circumference and asthma

Pediatric Pulmonology
Lisa MaltzRobert J Freishtat

Abstract

The association between obesity and asthma control/quality of life commonly relies on body mass index (BMI) as the anthropomorphic measure. Due to limitations of BMI and the existence of alternative measures, such as neck circumference (NC), we examined the association between NC and asthma control/quality of life, with particular attention to male-female differences. The AsthMaP-2 Project is an observational study of youth with physician-diagnosed asthma. NC was stratified according to age- and sex-specific cutoffs and associated with asthma control (via Asthma Control Test [ACT]) and quality of life (via Integrated Therapeutics Group [ITG]-Asthma Short Form). The mean ± SD age was 11.9 ± 3.6 years, and 53% were male (N = 116). The mean BMI percentile was at the 71 ± 28 percentile. Thirty-one participants (27%) met criteria for high NC. Males with high NC had significantly worse asthma control (P = 0.02) and lower quality of life than those with low NC. No similar association was found for females and the proportion of variability in ACT and ITG was best explained by BMI percentile. Conversely, for males, the proportion of variability in these scores explained by NC was larger than BMI percentile alone (Cohen's f(2)  = 0.04-0....Continue Reading

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Citations

Apr 26, 2017·Pediatric Pulmonology·Richard AutenTerry L Noah
Dec 29, 2016·Current Opinion in Allergy and Clinical Immunology·Erick Forno, Juan C Celedón
May 17, 2019·Human Molecular Genetics·Yadu GautamTesfaye B Mersha
Dec 17, 2019·American Journal of Respiratory and Critical Care Medicine·Bharati PrasadMihaela Teodorescu
Jan 19, 2018·International Journal of Endocrinology and Metabolism·Mostafa HosseiniRoya Kelishadi
Apr 9, 2018·The Journal of Allergy and Clinical Immunology·Ubong PetersErick Forno

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