Sex Differences in Trajectories of Risk After Rehospitalization for Heart Failure, Acute Myocardial Infarction, or Pneumonia

Circulation. Cardiovascular Quality and Outcomes
Rachel P DreyerHarlan M Krumholz

Abstract

Women have an increased risk of rehospitalization in the immediate postdischarge period; however, few studies have determined how readmission risk dynamically changes on a day-to-day basis over the full year after hospitalization by sex and how these differences compare with the risk for mortality. We identified >3 000 000 hospitalizations of patients with a principal discharge diagnosis of heart failure, acute myocardial infarction, or pneumonia and estimated sex differences in the daily risk of rehospitalization/death 1 year after discharge from a population of Medicare fee-for-service beneficiaries aged 65 years and older. We calculated the (1) time required for adjusted rehospitalization/mortality risks to decline 50% from maximum values after discharge, (2) time required for the adjusted readmission risk to approach plateau periods of minimal day-to-day change, and (3) extent to which adjusted risks are greater among recently hospitalized patients versus Medicare patients. We identified 1 392 289, 530 771, and 1 125 231 hospitalizations for heart failure, acute myocardial infarction, and pneumonia, respectively. The adjusted daily risk of rehospitalization varied by admitting condition (hazard rate ratio for women versus m...Continue Reading

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Citations

Jun 8, 2018·Coronary Artery Disease·Leor PerlJan B Pietzsch
Feb 17, 2018·Circulation. Cardiovascular Quality and Outcomes·Niti R AggarwalJennifer H Mieres
Dec 6, 2017·American Journal of Respiratory and Critical Care Medicine·Peter K LindenauerHarlan M Krumholz
Nov 30, 2018·Women's Health Issues : Official Publication of the Jacobs Institute of Women's Health·Luke LamKazuma Nakagawa
Jan 17, 2021·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Alan C KwanSusan Cheng
Jun 21, 2021·Journal of Cardiac Failure·Haider J WarraichDavid J Whellan

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