Sex hormones and autoimmunity

Immunology Letters
Delia Almeida GonzálezAntonio Cabrera de León

Abstract

Autoimmune diseases occur more in women than in men, and this may be attributable to the role of estrogens. Androgens promote autoimmune diseases with a profile of type 1 cytokines, such as rheumatoid arthritis, whereas estrogens promote autoimmune diseases with a type 2 cytokine profile, like systemic lupus erythematosus. Both androgens and estrogens regulate the Th1/Th2 balance. Type 1 autoimmune diseases are improved when decrease type 1 cytokines (i.e. during fasting), or when there is a rise in type 2 cytokines (increased estrogens, as in pregnancy). Type 2 autoimmune diseases improve when type 2 cytokines are diminished (decreased estrogen, as in post-partum period) or when type 1 response is stimulated.

References

May 31, 1975·British Medical Journal·B J Bain, J M England
Jun 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·P KubesD N Granger
Jan 1, 1990·Scandinavian Journal of Rheumatology·J M HazesJ P Vandenbroucke
Dec 1, 1989·Journal of Reproductive Immunology·J Szekeres-BarthoG Chaouat
Oct 1, 1989·Immunology Letters·J Szekeres-BarthoG Chaouat
May 18, 1985·British Medical Journal·F G McDonald, M M Ferguson
Feb 1, 1985·Journal of Reproductive Immunology·A N SulkeP J Wood
Oct 21, 1985·FEBS Letters·M M Ferguson, F G McDonald
Nov 1, 1972·The Journal of Experimental Medicine·D Eidinger, T J Garrett
Jan 1, 1994·Life Sciences·T GiglioS Costantini
Jun 11, 1996·Proceedings of the National Academy of Sciences of the United States of America·G G KuiperJ A Gustafsson
Nov 1, 1996·Clinical and Experimental Immunology·N KandaK Tamaki
Nov 14, 1997·American Journal of Reproductive Immunology : AJRI·J K MaskillA I Blakemore
Mar 14, 1998·FEBS Letters·W P BentenF Wunderlich
Feb 9, 1999·The Journal of Allergy and Clinical Immunology·N Kanda, K Tamaki
Jul 23, 1999·Annals of the New York Academy of Sciences·M Ostensen
Sep 30, 1999·Current Opinion in Rheumatology·R G Lahita
Nov 26, 1999·Circulation Research·M García-DuránA López-Farré
Apr 26, 2000·Clinical Immunology : the Official Journal of the Clinical Immunology Society·V RiderN I Abdou
May 17, 2000·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·G KlingerG Klinger
Jun 3, 2000·American Journal of Reproductive Immunology : AJRI·L FlynnC O'Farrelly
Jun 28, 2000·European Journal of Endocrinology·J A Girón-GonzálezL Escobar
Jun 30, 2000·Human Reproduction Update·M Beato, J Klug
Dec 6, 2000·The Journal of Clinical Investigation·E PeevaB Diamond
Feb 28, 2001·Experimental Gerontology·V R PorterR B Effros
Mar 29, 2001·American Journal of Reproductive Immunology : AJRI·A BoumanM M Faas

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Citations

Dec 30, 2011·Journal of Assisted Reproduction and Genetics·Vasileios D Sioulas, Clarisa R Gracia
Sep 10, 2011·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Divaker ChoubeyHongzhu Liu
Feb 19, 2011·Journal of Biomedicine & Biotechnology·Maria Gulinello, Chaim Putterman
Nov 25, 2011·Infectious Diseases in Obstetrics and Gynecology·Bryan Larsen, Joseph Hwang
Oct 15, 2011·PloS One·Victoria Wahl-JensenPeter B Jahrling
Jun 10, 2014·Iranian Red Crescent Medical Journal·Mohammad AbasiMehrdad Hajilooi
Mar 20, 2013·Clinical Immunology : the Official Journal of the Clinical Immunology Society·Kerstin Hellwig, Jorge Correale
Sep 15, 2015·International Journal of Cancer. Journal International Du Cancer·Ikuko KatoMichael S Simon
Feb 5, 2013·Journal of Autoimmunity·Ana LleoPietro Invernizzi
Jul 31, 2012·Gastroenterology·Hamed KhaliliAndrew T Chan
Mar 24, 2012·Autoimmunity Reviews·Harry E PeeryWarren G Foster
Apr 7, 2012·Clinics and Research in Hepatology and Gastroenterology·Cumali EfeErsan Ozaslan
Dec 24, 2011·Autoimmunity Reviews·Grant C Hughes
Dec 17, 2011·Autoimmunity Reviews·Tai-Ping Lee, Bor-Luen Chiang
Dec 17, 2011·Autoimmunity Reviews·Cecilia Chighizola, Pier Luigi Meroni
May 10, 2015·Clinical Immunology : the Official Journal of the Clinical Immunology Society·Andres GomezVeena Taneja
Oct 5, 2012·Annals of Neurology·Jorge CorrealeMaría C Ysrraelit
Mar 22, 2016·The Journal of Clinical Investigation·Nadine DraginSonia Berrih-Aknin
Feb 28, 2015·Aging Cell·Carmen Giefing-KröllBeatrix Grubeck-Loebenstein
Apr 23, 2016·Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society·Sema Ciftci DogansenSema Yarman
Mar 13, 2012·International Immunopharmacology·Xiaojuan LiShuwen Liu
Jul 10, 2012·Immunology Letters·Antonio Cabrera de LeónBuenaventura Brito Díaz
Dec 30, 2014·Cellular Immunology·Kira RubtsovaAnatoly V Rubtsov
Apr 20, 2014·Frontiers in Endocrinology·Damián MuzzioFederico Jensen
May 5, 2016·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·Anders H KvernelandBirgit Sawitzki
Jun 14, 2016·American Journal of Reproductive Immunology : AJRI·Nayoung SungJoanne Kwak-Kim
Aug 18, 2012·Autoimmune Diseases·Susan Yung, Tak Mao Chan
Sep 12, 2016·Journal of the American Academy of Dermatology·Khalaf KridinReuven Bergman
Jun 7, 2017·American Journal of Reproductive Immunology : AJRI·Li-Ling WangAi-Hua Liao
Nov 9, 2011·Lupus·G Zandman-GoddardY Shoenfeld
Mar 25, 2015·Lupus·I JochmanováI Lazúrová
Aug 5, 2017·Inflammatory Bowel Diseases·Kimberley W J van der SlootBehrooz Z Alizadeh

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