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Sex-Related Differences in Impact on Safety of Pharmacogenetic Profile for Colon Cancer Patients Treated with FOLFOX-4 or XELOX Adjuvant Chemotherapy

Scientific Reports

Aug 8, 2019

Annamaria RuzzoMauro Magnani

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Abstract

Polymorphisms contribute to inter-individual differences and show a promising predictive role for chemotherapy-related toxicity in colon cancer (CC). TOSCA is a multicentre, randomized, non-inferiority, phase III study conducted in high-risk stage II/stage III CC patients treated with 6...read more

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Alleles
Biological Markers
Gene Deletion
Glutaral
Interleukin-4
Kidney Failure, Chronic
Male Population Group
Randomization
Woman
Chemotherapy, Adjuvant
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Sex-Related Differences in Impact on Safety of Pharmacogenetic Profile for Colon Cancer Patients Treated with FOLFOX-4 or XELOX Adjuvant Chemotherapy

Scientific Reports

Aug 8, 2019

Annamaria RuzzoMauro Magnani

PMID: 31395900

DOI: 10.1038/s41598-019-47627-1

Abstract

Polymorphisms contribute to inter-individual differences and show a promising predictive role for chemotherapy-related toxicity in colon cancer (CC). TOSCA is a multicentre, randomized, non-inferiority, phase III study conducted in high-risk stage II/stage III CC patients treated with 6...read more

Mentioned in this Paper

Alleles
Biological Markers
Gene Deletion
Glutaral
Interleukin-4

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