Sex-specific determinants of serum 25-hydroxyvitamin D3 concentrations in an elderly German cohort: a cross-sectional study

Nutrition & Metabolism
Alexandra Jungert, Monika Neuhäuser-Berthold

Abstract

Considering the suggested link between vitamin D insufficiency and several chronic diseases, attention should be given to approaches for improving vitamin D status. Elderly subjects are regarded as a high-risk group for developing an insufficient vitamin D status. Socioeconomic, dietary, lifestyle and environmental factors are considered as influencing factors, whereupon sex differences in predictors of vitamin D status are rarely investigated. The purpose of this study is to identify the main predictors of serum 25-hydroxyvitamin D3 [25(OH)D3] concentrations in elderly subjects by taking into account potential sex differences. This is a cross-sectional study in 162 independently living German elderly aged 66 to 96 years. Serum 25(OH)D3 concentrations were assessed by an electrochemiluminescence immunoassay. Multiple regression analyses were performed to identify predictors of 25(OH)D3 concentrations stratified by sex. Median 25(OH)D3 concentration was 64 nmol/L and none of the subjects had 25(OH)D3 concentrations < 25 nmol/L. In women, intact parathyroid hormone (iPTH) (β = -0.323), % total body fat (β = -0.208), time spent outdoors (β = 0.328), month of blood sampling (β = 0.229) and intake of vitamin D supplements (β = 0.172...Continue Reading

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Citations

Jun 14, 2015·Endocrinología y nutrición : órgano de la Sociedad Española de Endocrinología y Nutrición·Raif M BotrosLaila M Hendawy
Jan 4, 2017·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Massimiliano VasileClara Crescioli
Jan 24, 2017·The Journal of Nutrition, Health & Aging·C TrevisanG Sergi
Jan 14, 2021·Biology of Sex Differences·Maria Luisa DupuisElena Ortona
Feb 6, 2020·Deutsches Ärzteblatt International·Alexandra JungertSabine Rohrmann

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