Sex-specific gene expression in preimplantation mouse embryos

Genome Biology
Guy S Eakin, Anna-Katerina Hadjantonakis

Abstract

The 3.5-day-old blastocyst-stage mouse embryo consists of two tissues and contains approximately 60 cells. This tiny structure has now been observed to express nearly 600 genes in a sex-specific fashion, including at least one gene (Rhox/Pem) expressed only in females from their paternal X chromosome.

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Citations

Jan 27, 2012·Biology of Sex Differences·Tao SunJoshua B Rubin
May 1, 2010·Reproduction : the Official Journal of the Society for the Study of Fertility·James A MacLean, Miles F Wilkinson
Feb 3, 2016·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Jacques Balthazart
Jun 25, 2014·Biochemical and Biophysical Research Communications·Stéphanie Olivier-Van StichelenJohn A Hanover
May 16, 2019·Nature·Michelle M ChanJonathan S Weissman
May 26, 2020·Neuroscience and Biobehavioral Reviews·Jacques Balthazart
Aug 19, 2006·Developmental Biology·Joanne L ThorvaldsenMarisa S Bartolomei

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Methods Mentioned

BETA
transgenic
reverse transcription PCR
PCR

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