PMID: 9420809Jul 1, 1995Paper

Sex specific issues relating to nuclear cardiology

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
L L Johnson

Abstract

Coronary heart disease is a major source of morbidity and mortality in women. Despite the importance of this health problem, women in general have not received the same degree of aggressiveness in diagnosis and treatment as men have received. Contributing to underdiagnosis and undertreatment in women include the results of the Framingham study, which showed that women with angina have better prognoses than men, and the results of multicenter percutaneous transluminal coronary angioplasty and coronary artery bypass grafting trials, which showed that women have higher morbidity and mortality rates in the periprocedure periods. These higher morbidity and mortality rates can largely be explained by the older ages of women when they have symptomatic coronary heart disease and the attendant higher incidence of comorbid diseases in an elderly population. Because of the cardiovascular protective effects of estrogen, the incidence of disease of the epicardial coronary arteries in the absence of significant risk factors in premenopausal women is very low despite the fairly high incidence of chest pain syndromes. Some of these women may have endothelial dysfunction, some small vessel disease, and some may have the visceral pain syndrome. ...Continue Reading

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Citations

Dec 23, 1999·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·L J ShawD D Miller
Oct 12, 1999·Radiographics : a Review Publication of the Radiological Society of North America, Inc·T L AngtuacoH Hricak
Dec 16, 2010·Circulation·Priya Kohli, Martha Gulati

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