PMID: 9170465Jun 1, 1997Paper

Sex steroid receptors and human parturition

Obstetrics and Gynecology
M RezapourU Ulmsten

Abstract

To investigate the correlation between sex steroid hormones and their receptors during normal and dysfunctional labor. Myometrial and decidual biopsies along with maternal and cord blood samples were taken from women with or without labor activity. Estrogen and progesterone receptor contents in myometrium and decidua were determined by enzyme immunoassay, and hormone concentrations were analyzed by radioimmunoassay. In the lower segment of the uterus, the progesterone receptor concentrations of myometrium were significantly lower in oxytocin-resistant dystocia compared with those of normal labor and before labor (P < .04, P < .005, respectively). No significant difference was found in the estrogen receptors contents in the groups studied. The progesterone receptors of myometrium from the upper segment showed higher concentrations in active labor compared with those before labor and oxytocin-resistant labor (P <.01, P < .05, respectively). Estrogen receptors from the upper segment showed no significant difference in these regards. There was no difference in peripheral and myometrial sex hormone levels in the groups studied. These data suggest that, in the human, 1) oxytocin-resistant labor is associated with low levels of proges...Continue Reading

References

Jun 1, 1975·The Journal of Clinical Endocrinology and Metabolism·D V IllingworthG Mikhail
Jul 1, 1979·The Journal of Clinical Endocrinology and Metabolism·G Giannopoulos, D Tulchinsky
Apr 1, 1978·The Journal of Clinical Endocrinology and Metabolism·F BayardE E Baulieu
Nov 30, 1990·The Journal of Steroid Biochemistry and Molecular Biology·T PadayachiS M Joubert
Apr 1, 1984·The Journal of Clinical Endocrinology and Metabolism·S W WalshM J Novy
Nov 1, 1984·Acta Physiologica Scandinavica·M BixoB Winblad
Mar 1, 1956·The American Journal of Anatomy·A CSAPO

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Citations

Jun 5, 2003·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Shirley AstleSteven Thornton
Oct 12, 2000·BJOG : an International Journal of Obstetrics and Gynaecology·M J Luckas, S Wray
Jan 15, 1998·Lancet·L B Schwartz
Jan 9, 2007·BJOG : an International Journal of Obstetrics and Gynaecology·R RomeroM Mazor
Dec 3, 2009·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Francesca GotschLami Yeo
Aug 9, 2006·American Journal of Obstetrics and Gynecology·Alyssa A MillsAmy P Murtha
Sep 25, 2001·American Journal of Obstetrics and Gynecology·D Henderson, T Wilson
May 4, 2004·Journal of the Society for Gynecologic Investigation·Sam Mesiano
Apr 5, 2019·Reproduction, Fertility, and Development·Marina IlicicJonathan W Paul
Feb 13, 2020·Reproductive Sciences·Marina IlicicJonathan W Paul
Jun 19, 2013·Journal of Perinatal Medicine·Jennifer Lam-RachlinTinnakorn Chaiworapongsa
May 26, 2017·BioMed Research International·Marina IlicicJonathan W Paul

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