Sexuality and fertility in long-term survivors of testicular cancer

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Y AraiO Yoshida

Abstract

We assessed the impact of different treatment modalities on sexuality and fertility in long-term survivors of testicular cancer. The sample consisted of 85 testicular cancer patients, of whom 19 had undergone chemotherapy with retroperitoneal lymph node dissection (RPLND), 15 had received chemotherapy only, 42 had received infradiaphragmatic radiotherapy, and nine had received surveillance therapy. The questionnaire reported sexual function, marital status, and issues related to fertility and childbearing. One fourth to one half reported some type of sexual impairment in each group. The only significant difference was that approximately 70% of men with RPLND reported inability of ejaculation and a greater decline in semen volume, which is expected. The most striking finding is that the rates and nature of sexual dysfunction of surveillance patients were similar to other treatment groups, except for ejaculatory function. The highest rates of infertility distress were observed in chemotherapy patients. These data suggest that sexual dysfunction and infertility represent the major persisting side effects, even years after diagnosis. The hypothesis that surveillance patients have fewer sexual problems is not upheld in this study.

Citations

Nov 14, 1997·International Journal of Urology : Official Journal of the Japanese Urological Association·Y AraiY Suzuki
Sep 27, 2000·Current Opinion in Urology·M KuczykU Jonas
Jan 26, 2005·Psycho-oncology·Jane TurnerUNKNOWN National Cancer Control Initiative, Melbourne, Australia
Dec 1, 1999·Current Opinion in Urology·S D FossåC F Haaland
Jan 5, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·F JolyM Henry-Amar
Jul 13, 1999·Medical and Pediatric Oncology·J Byrne
Nov 3, 2005·Journal of the National Cancer Institute·Marianne BrydøyOlav Dahl
Sep 22, 2005·International Journal of Urology : Official Journal of the Japanese Urological Association·Eiji HisamatsuHideyuki Akaza
Oct 28, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Philip Blach RossenHans von der Maase
Sep 8, 2012·Journal of Cancer Survivorship : Research and Practice·Anne C KirchhoffKen R Smith
Jun 11, 2011·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Rebecca PenroseBogda Koczwara
Dec 21, 2017·Reproductive Medicine and Biology·Itsuto HamanoChikara Ohyama
Aug 24, 2019·Frontiers in Endocrinology·Francesco PiercontiAlfredo Pontecorvi
Apr 8, 2020·Journal of Adolescent and Young Adult Oncology·Brigitte GerstlAntoinette Anazodo
Dec 22, 1999·International Journal of Cancer. Journal International Du Cancer·M DeSantisJ Pont
Jun 9, 1999·British Journal of Cancer·J T HartmannC Bokemeyer
Jan 31, 2004·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Arun Rajagopal, Eduardo D Bruera
Feb 27, 2018·International Journal of Urology : Official Journal of the Japanese Urological Association·Masahiro KurobeHiroyuki Nishiyama
Oct 24, 2018·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Jennifer A SoonCarmel Pezaro
Aug 24, 2001·Cancer·A L McKee, L R Schover
Jul 24, 2008·Journal of Cancer Survivorship : Research and Practice·Brad J ZebrackTammy S Weitzman
Oct 6, 2011·Arhiv za higijenu rada i toksikologiju·Marija GamulinVesna Bišof
Apr 4, 2015·International Journal of Molecular Sciences·Eva TvrdaNawaf Alkuhaimi
Aug 16, 2017·Journal of Health Psychology·Greer A RaggioJennifer Moye
Mar 17, 2011·Reproductive Medicine and Biology·Kohei Yamaguchi, Masato Fujisawa
Nov 26, 2002·International Journal of Urology : Official Journal of the Japanese Urological Association·Norio NonomuraTsuneharu Miki
Aug 11, 2020·The World Journal of Men's Health·Koichi OkadaNorio Nonomura
Jun 24, 2010·Journal of Cancer Survivorship : Research and Practice·Christopher KimYawei Zhang
Nov 2, 2020·International Journal of Urology : Official Journal of the Japanese Urological Association·Juntaro KoyamaAkihiro Ito
Jul 20, 2002·International Journal of Radiation Oncology, Biology, Physics·Luca IncrocciA Koos Slob
Jul 16, 2021·Therapeutic Advances in Medical Oncology·Ciara Conduit, Ben Tran
Dec 19, 2003·The Urologic Clinics of North America·Manish I PatelJoel Sheinfeld
Jul 20, 2021·International Journal of Urology : Official Journal of the Japanese Urological Association·Shinichi YamashitaYoichi Arai
Sep 5, 1998·The Urologic Clinics of North America·P J TurekP R Carroll
Jul 24, 2007·Critical Reviews in Oncology/hematology·R J GrollM A S Jewett
May 6, 2021·Minerva Urology and Nephrology·Vincenzo FavillaAldo E Calogero

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