Sexually transmitted infections and pre-exposure prophylaxis: challenges and opportunities among men who have sex with men in the US

AIDS Research and Therapy
Hyman M Scott, Jeffrey D Klausner

Abstract

Pre-Exposure Prophylaxis (PrEP) has shown high efficacy in preventing human immunodeficiency virus (HIV) infection among men who have sex with men (MSM) in several large clinical trials, and more recently in "real world" reports of clinical implementation and a PrEP demonstration project. Those studies also demonstrated high bacterial sexually transmitted infection (STI) incidence and raised the discussion of how PrEP may impact STI control efforts, especially in the setting of increasing Neisseria gonorrhoeae antimicrobial resistance and the increase in syphilis cases among MSM. Here, we discuss STIs as a driver of HIV transmission risk among MSM, and the potential opportunities and challenges for STI control afforded by expanded PrEP implementation among high-risk MSM.

References

May 30, 2003·American Journal of Public Health·Beryl A KoblinUNKNOWN EXPLORE Study Team
Mar 24, 2004·Nature Reviews. Microbiology·Shannon R Galvin, Myron S Cohen
Apr 27, 2005·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Susan P BuchbinderBeryl A Koblin
Jun 7, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Charlotte K KentJeffrey D Klausner
Mar 4, 2006·AIDS·Beryl A KoblinSusan Buchbinder
Mar 24, 2006·Sexually Transmitted Diseases·Stuart M Berman, Myron S Cohen
Apr 16, 2009·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Nicola M ZetolaJeffrey D Klausner
Nov 26, 2009·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Kyle T BernsteinJeffrey D Klausner
Nov 26, 2010·The New England Journal of Medicine·Robert M GrantUNKNOWN iPrEx Study Team
Feb 19, 2011·AIDS and Behavior·Susan P Buchbinder, Albert Liu
Jan 15, 2014·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Hyman M ScottSusan P Buchbinder
Mar 22, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Monica E PattonHillard Weinstock
Jun 15, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Marc M SolomonUNKNOWN iPrEx Study Team
Jun 24, 2015·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Ekkehard C BeckBrian Mustanski
Sep 4, 2015·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Kimberly A Koester, Robert M Grant
Sep 4, 2015·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jonathan E VolkC Bradley Hare
Oct 16, 2015·MMWR. Morbidity and Mortality Weekly Report·Sophie WoolstonMatthew R Golden
Nov 4, 2015·JAMA : the Journal of the American Medical Association·Robert D KirkcaldyJohn R Papp
Dec 2, 2015·The New England Journal of Medicine·Jean-Michel MolinaUNKNOWN ANRS IPERGAY Study Group
Dec 4, 2015·MMWR. Recommendations and Reports : Morbidity and Mortality Weekly Report. Recommendations and Reports·William A BowerUNKNOWN Centers for Disease Control and Prevention (CDC)

❮ Previous
Next ❯

Citations

Dec 21, 2016·Journal of Behavioral Medicine·Sarit A Golub, Kristi E Gamarel
Jan 6, 2017·Sexual Health·Abigail W BatchelderConall O'Cleirigh
Feb 21, 2018·Current HIV/AIDS Reports·Sarit A Golub
Dec 7, 2017·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Viktor MravčíkIvo Procházka
May 23, 2018·Sexually Transmitted Diseases·Trang Quyen NguyenStephanie E Cohen
Oct 18, 2018·AIDS Education and Prevention : Official Publication of the International Society for AIDS Education·Matthew A HeveyAndrew E Petroll
Jan 8, 2019·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Lisa B Hightow-WeidmanDarrell Wheeler
Oct 29, 2019·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Kenneth H Mayer, Lao-Tzu Allan-Blitz
Nov 17, 2016·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Julia L MarcusJonathan E Volk
Sep 15, 2016·Expert Review of Anti-infective Therapy·Chelsea P Roberts, Jeffrey D Klausner
Sep 2, 2017·Transgender Health·Virginia ZalazarM Eugenia Socías
Feb 22, 2018·Sexually Transmitted Diseases·Sara A VasilenkoJoshua G Rosenberger
May 12, 2018·Archives of Sexual Behavior·Katherine Frank
May 18, 2018·Canada Communicable Disease Report = Relevé Des Maladies Transmissibles Au Canada·Y ChoudhriJ Aho
Apr 18, 2016·The Journal of the Association of Nurses in AIDS Care : JANAC·Joachim G Voss, James Les L Harmon
Nov 21, 2020·The Lancet. Gastroenterology & Hepatology·Fengyi JinAndrew E Grulich
May 1, 2021·International Journal of Environmental Research and Public Health·Iga StokłosaPiotr Gorczyca
Sep 4, 2017·Medicina clínica·Alfonso Cabello, Miguel Górgolas
Feb 25, 2021·Journal of the American Association of Nurse Practitioners·Janice M Stockton

❮ Previous
Next ❯

Methods Mentioned

BETA
nucleic acid amplification

Related Concepts

Related Feeds

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.