Sexually transmitted infections and use of contraceptives in women living with HIV in Denmark - the SHADE cohort

BMC Infectious Diseases
Kristina ThorsteinssonAnne-Mette Lebech

Abstract

No Danish guidelines for screening of sexually transmitted infections (STIs) in women living with HIV (WLWH) exist, except for annual syphilis testing. Drug-drug interaction between hormonal contraceptives and some types of highly active antiretroviral therapy (HAART) occurs. We assessed prevalence of STIs, contraceptive choices and predictors of condom use in a cohort of WLWH in Denmark. WLWH consecutively enrolled during their outpatient visits from 2011 to 2012. Gynaecological examination and an interview were performed at entry and 6-month follow-up. Inclusion criteria were HIV-1 infection and ≥ 18 years of age. Exclusion criteria were pregnancy, alcohol- or drug abuse impeding adherence to the protocol. At entry, participants were tested (and where appropriate, treated according to guidelines) for Chlamydia trachomatis, Neisseria gonorrhoeae, syphilis, and herpes simplex (HSV-1 and HSV-2). At follow-up, predictors of condom use were estimated in sexually active WLWH. In total, 334 of the 1,392 eligible WLWH in Denmark were included (median age and HIV duration: 42.5 and 11.3 years). Chlamydia trachomatis was present in four individuals (1 %), and six (2 %) tested positive for HSV-2 by PCR. None were positive for Neisseria ...Continue Reading

References

Aug 20, 2003·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·H Westh, H J Kolmos
Sep 19, 2008·International Journal of Epidemiology·Niels ObelHenrik T Sørensen
Jan 22, 2010·The New England Journal of Medicine·C CelumUNKNOWN Partners in Prevention HSV/HIV Transmission Study Team
Jun 15, 2010·Current Opinion in HIV and AIDS·Helen Ward, Minttu Rönn
Mar 11, 2011·PloS One·Clare TantonDeborah Watson-Jones
Jul 20, 2011·The New England Journal of Medicine·Myron S CohenUNKNOWN HPTN 052 Study Team
Aug 4, 2011·Scandinavian Journal of Public Health·Carsten Bøcker Pedersen
Sep 25, 2012·HIV Medicine·A HughesF Boag
Dec 20, 2012·Sexually Transmitted Diseases·Sebastian VidelaUNKNOWN HIV-HPV Study Group
Dec 29, 2012·Sexually Transmitted Infections·Kirsten Salado-RasmussenNiels Obel
Feb 22, 2013·Expert Opinion on Drug Metabolism & Toxicology·Alice Tseng, Cara Hills-Nieminen
Oct 4, 2013·Journal of the International AIDS Society·Mona R LoutfyUNKNOWN Women for Positive Action
May 9, 2014·AIDS·Pragna PatelJonathan Mermin
Jun 26, 2014·Infectious Diseases in Obstetrics and Gynecology·Tara PertiAnna Wald
Sep 23, 2014·PeerJ·Katharina SprengerUNKNOWN Swiss HIV Cohort Study
Oct 22, 2014·Clinical Pharmacokinetics·Victoria TittleNneka Nwokolo
Dec 3, 2014·The Pediatric Infectious Disease Journal·Pamela S BrownsteinAndres F Camacho-Gonzalez
Mar 15, 2015·International Journal of STD & AIDS·Héléne PéréUNKNOWN ANRS EP24 study group

❮ Previous
Next ❯

Citations

Aug 18, 2018·Current Epidemiology Reports·Noah Kojima, Jeffrey D Klausner
Aug 24, 2019·BMC Infectious Diseases·Kristina ThorsteinssonJesper Bonde
Sep 15, 2018·Open Forum Infectious Diseases·Andreas KnudsenAndreas Kjaer
Sep 9, 2017·BMC Research Notes·Anne Marie Rosendahl MadsenJørgen Skov Jensen

❮ Previous
Next ❯

Methods Mentioned

BETA
contraception
PCR

Software Mentioned

SAS
EpiData Entry
SHADE

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.