SGLT2 inhibitors: What role do they play in heart failure with reduced ejection fraction?

The Nurse Practitioner
Christy McDonald LenahanFrances Stueben


Sodium-glucose cotransporter-2 (SGLT2) inhibitors can decrease risk for heart failure in patients with type 2 diabetes and can decrease risk of major cardiovascular events in patients with heart failure (HF) and diabetes. Specific SGLT2 inhibitors can also decrease major cardiovascular events in patients with HF only.


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