SH3 domains. Minding your p's and q's

Current Biology : CB
B J Mayer, M J Eck


SH3 domains mediate many important protein-protein interactions. The molecular basis of the binding of these domains to their ligands has been revealed, making it possible to identify SH3-binding sites in new proteins.


Nov 1, 1996·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·D E Warnock, S L Schmid
Jun 7, 1996·Biochimica Et Biophysica Acta·M T Brown, J A Cooper
Mar 24, 2005·Journal of Molecular Biology·Magdalena WisniewskaRichard A Engh
Feb 22, 2003·Journal of Molecular Biology·José R PiresRalf Erdmann
Jun 4, 1999·Progress in Biophysics and Molecular Biology·L E Samelson
Feb 5, 1998·Brain Research. Molecular Brain Research·P VaccaroF Benfenati
Oct 24, 2000·Biology of the Cell·B Ciapa, S Chiri
Oct 6, 1997·Cellular Signalling·N Dunant, K Ballmer-Hofer
Oct 6, 1997·Cellular Signalling·R M Scaife, R L Margolis
Aug 28, 1998·Current Opinion in Cell Biology·S L SchmidP De Camilli
Jul 20, 2002·The International Journal of Biochemistry & Cell Biology·Pier Paolo Di Fiore, Giorgio Scita
Jul 15, 2009·Nature Immunology·Renaud LesournePaul E Love
Sep 5, 2002·The Plant Journal : for Cell and Molecular Biology·Bernard C-H LamE Blumwald
Feb 1, 1996·The Journal of Cell Biology·G WeskampC P Blobel
Apr 1, 1997·Molecular Biology of the Cell·C RedheadJ C Edwards
Jan 6, 2006·Molecular Biology of the Cell·Helena FriesenBrenda Andrews
Sep 26, 2000·Human Molecular Genetics·H Tanahashi, T Tabira
Apr 23, 1999·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·F BenfenatiS Giovedí
Apr 19, 2008·Journal of Synchrotron Radiation·Eun Young Park, Hyun Kyu Song
Apr 23, 2002·Journal of Virology·Eric O Freed
Feb 26, 1998·American Journal of Respiratory and Critical Care Medicine·T J Torphy
Feb 5, 2014·Biological & Pharmaceutical Bulletin·Yuichi Sekine
Oct 29, 1997·Proceedings of the National Academy of Sciences of the United States of America·F OnofriF Benfenati
Jul 8, 1997·Proceedings of the National Academy of Sciences of the United States of America·A J da SilvaC E Rudd
Jan 24, 2002·Proceedings of the National Academy of Sciences of the United States of America·Dimiter G DemirovEric O Freed
Jul 22, 1998·Proceedings of the National Academy of Sciences of the United States of America·J LiuC E Rudd


Jul 29, 1994·Journal of Molecular Biology·E S Cedergren-ZeppezauerC E Schutt
Aug 16, 1994·Proceedings of the National Academy of Sciences of the United States of America·G ChengD Baltimore
Jun 7, 1994·Proceedings of the National Academy of Sciences of the United States of America·H SumimotoK Takeshige
May 6, 1993·Nature·F McCormick

Related Concepts

Gene Products, Protein
Proto-Oncogene Protein pp60 (c-src)
Plasma Protein Binding Capacity
Protein Conformation

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Synapse Loss as Therapeutic Target in MS

As we age, the number of synapses present in the human brain starts to decline, but in neurodegenerative diseases this occurs at an accelerated rate. In MS, it has been shown that there is a reduction in synaptic density, which presents a potential target for treatment. Here is the latest research on synapse loss as a therapeutic target in MS.

Artificial Intelligence in Cardiac Imaging

Artificial intelligence (ai) techniques are increasingly applied to cardiovascular (cv) medicine in cardiac imaging analysis. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

Social Learning

Social learning involves learning new behaviors through observation, imitation and modeling. Follow this feed to stay up to date on the latest research.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Single Cell Chromatin Profiling

Techniques like ATAC-seq and CUT&Tag have the potential to allow single cell profiling of chromatin accessibility, histones, and TFs. This will provide novel insight into cellular heterogeneity and cell states. Discover the latest research on single cell chromatin profiling here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.