Shape analysis of hypertrophic and hypertensive heart disease using MRI-based 3D surface models of left ventricular geometry

Medical Image Analysis
Siamak ArdekaniLaurent Younes

Abstract

The focus of this study was to develop advanced mathematical tools to construct high-resolution 3D models of left-ventricular (LV) geometry to evaluate focal geometric differences between patients with hypertrophic cardiomyopathy (HCM) and hypertensive heart disease (HHD) using cardiac magnetic resonance (MR) cross-sectional images. A limiting factor in 3D analysis of cardiac MR cross-sections is the low out-of-plane resolution of the acquired images. To overcome this problem, we have developed a mathematical framework to construct a population-based high-resolution 3D LV triangulated surface (template) in which an iterative matching algorithm maps a surface mesh of a normal heart to a set of cross-sectional contours that were extracted from short-axis cine cardiac MR images of patients who were diagnosed with either HCM or HHD. A statistical analysis was conducted on deformations that were estimated at each surface node to identify shape differences at end-diastole (ED), end-systole (ES), and motion-related shape variation from ED to ES. Some significant shape difference in radial thickness was detected at ES. Differences of LV 3D surface geometry were identified focally on the basal anterior septum wall. Further research is n...Continue Reading

References

Jan 16, 1999·Annals of Internal Medicine·A PellicciaB J Maron
Jul 10, 1999·Journal of the American College of Cardiology·E O WeinbergB H Lorell
Feb 5, 2003·IEEE Transactions on Medical Imaging·Kate McLeishReza Razavi
Feb 5, 2003·IEEE Transactions on Medical Imaging·Alejandro F FrangiWiro J Niessen
Sep 12, 2003·The New England Journal of Medicine·Barry J Maron
Nov 18, 2004·JAMA : the Journal of the American Medical Association·Julius M Gardin, Michael S Lauer
Jun 18, 2005·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Steffen E PetersenStefan Neubauer
Jan 15, 2008·IEEE Transactions on Visualization and Computer Graphics·Sebastien ValetteRémy Prost
Mar 27, 2009·Annals of Biomedical Engineering·Siamak ArdekaniLaurent Younes
Aug 12, 2009·Medical Image Analysis·Vicky Y WangMartyn P Nash
Jun 19, 2010·Journal of Cardiovascular Translational Research·Matthew WheelerEuan A Ashley
Jul 2, 2010·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Frank WeidemannStefan Störk
Sep 22, 2010·The American Journal of Cardiology·Valentina O PuntmannIngo Paetsch
Apr 26, 2011·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Sherif F NaguehUNKNOWN Society of Cardiovascular Computed Tomography
Feb 3, 2012·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Martin S Maron
Feb 22, 2012·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Radwa A NoureldinDavid A Bluemke
Sep 17, 2013·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Pau Medrano-GraciaAlistair A Young
Aug 28, 2014·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Pau Medrano-GraciaAlistair A Young
Nov 2, 2014·PloS One·Xingyu ZhangPau Medrano-Gracia

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Citations

Jan 20, 2017·IEEE Journal of Biomedical and Health Informatics·Avan SuinesiaputraPau Medrano-Gracia
Jan 8, 2017·Briefings in Bioinformatics·Guifang FuRongling Wu
Oct 3, 2020·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Shoon Hui ChuahYih Miin Liew

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