Shape analysis of the microcirculatory flow wave

Physiological Measurement
Leonardo BocchiM Bevilacqua

Abstract

The cardiovascular system and its alterations are a crucial aspect of physiology and medicine. Non-invasive assessment of the functional properties of circulation is of considerable interest to clinicians and physiologists. In this work we investigate the possibility of detecting alterations of the flow waveform in microcirculation, using non-invasive measurements based on a laser Doppler flowmeter. As a test case, we focus on the effect of ageing. Skin is warmed up to a fixed temperature (44 °C) during measurement, to increase blood flow. The shape of the perfusion waveform during each heart beat after the flow was stabilized was used to estimate dynamic parameters of the microcirculatory system. Both the wave rise time, defined as the delay between the diastolic minimum and the following systolic maximum, and the oscillation fraction, defined as the normalized difference between the maximum and minimum flow, present significant variation with age.

References

Jul 1, 1975·The American Journal of Cardiology·K ChatterjeeD Chonette
Oct 1, 1986·The American Journal of Physiology·V E Baracos, A L Goldberg
May 1, 1970·Circulation Research·N T KouchoukosD A McDonald
Sep 18, 1998·Bulletin of Mathematical Biology·M Bracic, A Stefanovska
Mar 21, 2002·Clinical and Experimental Pharmacology & Physiology·B A KingwellG L Jennings
Aug 30, 2005·Journal of Pharmacological and Toxicological Methods·Get Bee Yvonne-TeeAbdul Rashid Abdul Rahman
Feb 10, 2006·Physics in Medicine and Biology·P T ChaoY Y Lin Wang
Feb 18, 2006·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Gregg R McCordChristopher T Minson
Feb 10, 2009·Physiological Measurement·Alan Bernjak, Aneta Stefanovska
Apr 17, 2010·Physics Reports·Y ShiogaiP V E McClintock
May 10, 2011·Journal of Applied Physiology·Vienna E Brunt, Christopher T Minson
May 25, 2011·Physics in Medicine and Biology·L W SheppardA Stefanovska
Sep 13, 2011·Microvascular Research·A StefanovskaP V E McClintock
Jun 8, 2012·The Journal of Physiology·Vienna E Brunt, Christopher T Minson
Mar 30, 2013·Microvascular Research·A BandiniL Bocchi
Jun 25, 2013·Trends in Pharmacological Sciences·Matthieu Roustit, Jean-Luc Cracowski
Jul 25, 2013·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·Piotr KrutkiJan Celichowski
Oct 15, 2013·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·Hsin HsiuChih-Yu Chen
Nov 30, 2013·Journal of Healthcare Engineering·Andrea BandiniLeonardo Bocchi
Apr 23, 2014·Current Eye Research·Satoru TsudaToru Nakazawa

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Citations

Jan 13, 2017·Physiological Measurement·Michele SorelliLeonardo Bocchi

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