Shaping memory consolidation via targeted memory reactivation during sleep

Annals of the New York Academy of Sciences
Nicola Cellini, Alessandra Capuozzo

Abstract

Recent studies have shown that the reactivation of specific memories during sleep can be modulated using external stimulation. Specifically, it has been reported that matching a sensory stimulus (e.g., odor or sound cue) with target information (e.g., pairs of words, pictures, and motor sequences) during wakefulness, and then presenting the cue alone during sleep, facilitates memory of the target information. Thus, presenting learned cues while asleep may reactivate related declarative, procedural, and emotional material, and facilitate the neurophysiological processes underpinning memory consolidation in humans. This paradigm, which has been named targeted memory reactivation, has been successfully used to improve visuospatial and verbal memories, strengthen motor skills, modify implicit social biases, and enhance fear extinction. However, these studies also show that results depend on the type of memory investigated, the task employed, the sensory cue used, and the specific sleep stage of stimulation. Here, we present a review of how memory consolidation may be shaped using noninvasive sensory stimulation during sleep.

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Citations

Apr 30, 2019·Frontiers in Human Neuroscience·Nicola CelliniStephen B Simons
Nov 13, 2018·Psychopharmacology·Gürsel Çalışkan, Oliver Stork
Mar 21, 2019·Frontiers in Psychology·Nicola CelliniMichela Sarlo
Feb 13, 2020·Scientific Reports·Eitan SchechtmanKen A Paller
Jul 14, 2020·NPJ Science of Learning·Marlieke Tina Renée van Kesteren, Martijn Meeter
Feb 14, 2021·NPJ Science of Learning·Marlieke Tina Renée van Kesteren, Martijn Meeter
May 2, 2020·Schizophrenia Research·Flavio Fröhlich, Caroline Lustenberger
Mar 27, 2021·Communications Biology·Isabel C HutchisonPenelope A Lewis
Feb 12, 2019·Neuroscience·Heather D LucasKen A Paller

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