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Shared regulatory pathways reveal novel genetic correlations between grip strength and neuromuscular disorders

bioRxiv

Sep 13, 2019

Sreemol GokuladhasJustin Martin O'Sullivan

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Abstract

Background: Muscle weakness and muscle wasting can be a consequence of aging (sarcopenia) and neuromuscular disorders (NMD). Genome-wide association (GWA) studies have identified genetic variants associated with grip strength (GS, an inverse measure of muscle weakness) and NMD (multiple...read more

Mentioned in this Paper

Aging
Alcoholic Intoxication, Chronic
Alleles
Amyotrophic Lateral Sclerosis
Multiple Sclerosis
Muscle
Myasthenia Gravis
Neuromuscular Diseases
Mass Spectrometry
Substance Abuse Detection
13
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Shared regulatory pathways reveal novel genetic correlations between grip strength and neuromuscular disorders

bioRxiv

Sep 13, 2019

Sreemol GokuladhasJustin Martin O'Sullivan

DOI: 10.1101/765495

Abstract

Background: Muscle weakness and muscle wasting can be a consequence of aging (sarcopenia) and neuromuscular disorders (NMD). Genome-wide association (GWA) studies have identified genetic variants associated with grip strength (GS, an inverse measure of muscle weakness) and NMD (multiple...read more

Mentioned in this Paper

Aging
Alcoholic Intoxication, Chronic
Alleles
Amyotrophic Lateral Sclerosis
Multiple Sclerosis
13

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