Sheehan syndrome with reversible dilated cardiomyopathy.

Annals of Saudi Medicine
Bashir A LawayAbdul Hamid Zargar

Abstract

Cardiac abnormalities in patients with Sheehan syndrome are uncommon. A case of Sheehan syndrome with dilated cardiomyopathy is presented in whom hormone replacement with levothyroxine and prednisolone resulted in complete recovery of cardiomyopathy. A 25-year-old woman presented with lactation failure, secondary amenorrhea, features of hypothyroidism and a hypocortisol state following severe postpartum hemorrhage after her last child birth. She also had smear positive pulmonary tuberculosis. After starting antitubercular treatment, she developed shock, suggestive of hypocortisol crisis. Hormonal investigations revealed evidence of panhypopitutarism and magnetic resonance imaging revealed partial empty sella. Meanwhile echocardiography revealed evidence of dilated cardiomyopathy (DCM). The patient was given replacement therapy in the form of glucocorticoids and levothyroxine in addition to antitubercular treatment. She improved and on follow-up over a period of 7 months, the DCM completely reversed. To our knowledge this is the first report of reversible DCM in a patient with Sheehan syndrome.

References

Feb 15, 2001·The New England Journal of Medicine·I Klein, K Ojamaa
Sep 6, 2002·The Journal of Clinical Endocrinology and Metabolism·Ravinder GoswamiNandita Gupta
Jul 10, 2003·Autoimmunity Reviews·J Bruce SundstromAftab A Ansari
Aug 14, 2003·Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society·Anne Klibanski
Jul 1, 1954·American Journal of Obstetrics and Gynecology·H L SHEEHAN
Jul 9, 2004·Pituitary·Fahrettin Keleştimur
Aug 9, 2005·Fertility and Sterility·Abdul Hamid ZargarMir Iftikhar Bashir
Mar 8, 2006·International Journal of Cardiology·Kenji OkiMichinori Imazu
Jun 15, 2006·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Amish Parikh, Shereen Ezzat
May 1, 1996·Annals of Saudi Medicine·A H ZargarS Kour
Jan 16, 2008·Clinical Medicine : Journal of the Royal College of Physicians of London·Anish N ShahDai Thomas

❮ Previous
Next ❯

Citations

Jul 1, 2016·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Bashir Ahmad LawayRaiz Ahmad Misgar
Nov 10, 2010·Annals of Saudi Medicine·Sourabh Aggarwal
Mar 21, 2013·Circulation. Heart Failure·Shrenik DoshiVinay K Bahl
Feb 28, 2016·Circulation. Heart Failure·Yukinori IkegamiYukihiko Momiyama
Jun 16, 2019·Heart·Lucia BarisJolien W Roos-Hesselink
Sep 20, 2019·Acta Cardiologica·Pauwelijn VerhoestraeteVandekerckhove Hans
Apr 11, 2014·Journal of the Saudi Heart Association·A K M Monwarul IslamHumayra Jesmin
Jun 2, 2017·Experimental and Therapeutic Medicine·Lu LiangXiao-Li Zhang
Nov 7, 2017·European Heart Journal. Case Reports·Sunny D ShindePrafulla G Kerkar
Dec 6, 2011·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Shunzhong S Bao, Simon J Fisher

❮ Previous
Next ❯

Methods Mentioned

BETA
X-ray

Related Concepts

Related Feeds

Antitubercular Agents (ASM)

Antitubercular agents are pharmacologic agents for treatment of tuberculosis. Discover the latest research on antitubercular agents here.

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Antitubercular Agents

Antitubercular agents are pharmacologic agents for treatment of tuberculosis. Discover the latest research on antitubercular agents here.

Related Papers

Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology
T J BunchR I Gosman
Journal of the Chinese Medical Association : JCMA
Shu-Yi WangShih-Te Tu
Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology
Hatice Sebila DökmetaşOzlem Yonem
Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association
W MunzK Pollow
© 2021 Meta ULC. All rights reserved