PMID: 653500Feb 4, 1978Paper

Sheehan's syndrome presenting with hypothyroidism and hypo-adrenalism despite treatment with thyroxine and prednisone

South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
A C AsmalB Dayal

Abstract

A 35-year-old patient with Sheehan's syndrome presented with hypothyroidism and hypo-adrenalism despite having received treatment with regular daily L-thyroxine (0,3 mg) and prednisone (30 mg) for the preceding 12 months. Replacement of the prednisone with 37,5 mg cortisone acetate resulted in satisfactory control of the disease. The observations suggest that large doses of prednisone may interfere with thyroxine treatment.

Related Concepts

Related Feeds

Addison Disease

Addison's disease, also known as primary adrenal insufficiency and hypocortisolism, is a long-term endocrine disorder in which the adrenal glands do not produce enough steroid hormones. Discover the latest research on Addison's disease here.