Shielding effects of metallic encapsulations and radiographic contrast agents for catheter-based intravascular brachytherapy

Cardiovascular Radiation Medicine
R Nath, N Yue

Abstract

Both photon- and beta-emitting radionuclides for intravascular brachytherapy (IVB) are under active investigation for prevention of restenosis following conventional angioplasty with or without stents. High atomic number materials are usually present in the coronary vessels undergoing treatment in the form of metallic encapsulations, stents, calcified plaque, or radiographic contrast agent. The high atomic number materials are likely to interfere with the photons and betas and, thus, change the dosimetry in the treatment volume. The purpose of this study is to investigate the shielding effects caused by the presence of high atomic number materials in IVB. Dose rates at various distances in water, with and without the presence of various high atomic number materials, were calculated using Monte Carlo simulation techniques for photon and electron transport in extended media. The high atomic number materials investigated included titanium, stainless steel, calcified plaque, Hypaque, and Omnipaque. A wide range of monoenergetic photon and electron sources and several photon- and beta-emitting radionuclides, which have been under consideration for IVB, were used. The energy of the monoenergetic photon sources was in the range from 1...Continue Reading

Citations

Aug 22, 2007·Cardiovascular and Interventional Radiology·Krzysztof WilczekLech Poloński
Feb 1, 2003·Medical Physics·Omar Chibani, X Allen Li
Sep 2, 2014·Neurosurgical Focus·Kenan AlKhaliliPascal Jabbour
Dec 24, 2011·AJNR. American Journal of Neuroradiology·F BingA Weill
Dec 14, 2005·Brachytherapy·X Allen LiMohan Suntharalingam
May 7, 2002·Medical Physics·Omar Chibani, X Allen Li
Mar 20, 2002·Physics in Medicine and Biology·R A Fox

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