Shift and adapt: the costs and benefits of karyotype variations

Current Opinion in Microbiology
Aleeza C Gerstein, Judith Berman

Abstract

Variation is the spice of life or, in the case of evolution, variation is the necessary material on which selection can act to enable adaptation. Karyotypic variation in ploidy (the number of homologous chromosome sets) and aneuploidy (imbalance in the number of chromosomes) are fundamentally different than other types of genomic variants. Karyotypic variation emerges through different molecular mechanisms than other mutational events, and unlike mutations that alter the genome at the base pair level, rapid reversion to the wild type chromosome number is often possible. Although karyotypic variation has long been noted and discussed by biologists, interest in the importance of karyotypic variants in evolutionary processes has spiked in recent years, and much remains to be discovered about how karyotypic variants are produced and subsequently selected.

References

Dec 20, 2000·Antimicrobial Agents and Chemotherapy·K A MarrT C White
Nov 26, 2002·Proceedings of the National Academy of Sciences of the United States of America·Maitreya J DunhamDavid Botstein
May 14, 2003·The EMBO Journal·Richard J Bennett, Alexander D Johnson
Nov 26, 2003·Journal of Evolutionary Biology·L Hadany, T Beker
Jul 22, 2006·Science·Anna SelmeckiJudith Berman
Sep 28, 2006·PLoS Genetics·Aleeza C GersteinSarah P Otto
Oct 6, 2007·Critical Reviews in Biochemistry and Molecular Biology·Rodrigo S GalhardoSusan M Rosenberg
Mar 28, 2008·Molecular Microbiology·Anna SelmeckiJudith Berman
Jul 25, 2009·The Journal of Heredity·Aleeza C Gerstein, Sarah P Otto
Aug 25, 2009·Eukaryotic Cell·Kelly BouchonvilleJudith Berman
May 13, 2010·Molecular Systems Biology·Michael SpringerMarc W Kirschner
May 18, 2010·Integrative Biology : Quantitative Biosciences From Nano to Macro·Pravin K NaoghareJoon Myong Song
Sep 21, 2010·Cell·Eduardo M TorresAngelika Amon
Aug 20, 2011·Science·Jason M SheltzerAngelika Amon
Apr 12, 2012·Proceedings. Biological Sciences·Warren Albertin, Philippe Marullo
May 1, 2012·Nature Methods·Jiekai Chen, Duanqing Pei
Jul 19, 2012·Annual Review of Cell and Developmental Biology·Jake J Siegel, Angelika Amon
Oct 12, 2012·Biology Letters·Aleeza C Gerstein
Dec 1, 2012·Proceedings of the National Academy of Sciences of the United States of America·Avihu H YonaOrna Dahan
Feb 6, 2013·Seminars in Cell & Developmental Biology·Carl A Morrow, James A Fraser
Feb 14, 2013·Seminars in Cell & Developmental Biology·Giulia Rancati, Norman Pavelka
Mar 8, 2013·Molecular Biology of the Cell·Rebecca R ThorburnAngelika Amon
Apr 5, 2013·PLoS Genetics·Enikö ZörgöJonas Warringer
Jul 3, 2013·Proceedings of the National Academy of Sciences of the United States of America·Zhihao TanAimée M Dudley
Oct 15, 2013·Eukaryotic Cell·Riyad N H SeervaiRichard J Bennett
Mar 20, 2014·PLoS Biology·Benjamin D HarrisonJudith Berman
May 23, 2014·Proceedings of the National Academy of Sciences of the United States of America·Yuan O ZhuDmitri A Petrov
Jul 26, 2014·G3 : Genes - Genomes - Genetics·Elyse A Hope, Maitreya J Dunham
Nov 5, 2014·Genome Biology and Evolution·Dana J WohlbachAudrey P Gasch
Jan 30, 2015·Molecular Biology of the Cell·Cori A AndersonAmy S Gladfelter
Feb 14, 2015·Cell·Guangbo ChenRong Li
Mar 4, 2015·Nature·Anna M SelmeckiDavid Pellman

❮ Previous
Next ❯

Citations

Sep 14, 2016·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Yoav Ram, Lilach Hadany
Nov 1, 2016·Proceedings. Biological Sciences·Clara Bleuven, Christian R Landry
Feb 15, 2017·Evolution; International Journal of Organic Evolution·Aleeza C GersteinMeleah A Hickman
Oct 27, 2017·Molecular Biology and Evolution·Katya Kosheleva, Michael M Desai
Nov 3, 2016·Nature Communications·Johan HallinGianni Liti
Feb 27, 2018·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Ying WuBao Liu
Apr 18, 2020·Biological Reviews of the Cambridge Philosophical Society·Miguel A Naranjo-Ortiz, Toni Gabaldón
Feb 18, 2017·Biology·Tamara Potapova, Gary J Gorbsky
Feb 1, 2020·Nature Communications·Alaattin KayaVadim N Gladyshev

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.