Shift work and hypertension: Prevalence and analysis of disease pathways in a German car manufacturing company

American Journal of Industrial Medicine
Johan OhlanderKatja Radon

Abstract

Hypertension and cardiovascular disease (CVD) may share a similar pathophysiology. Despite shift workers' CVD excess risk, studies on shift work and hypertension are inconclusive. Blood pressure and shift status for 25,343 autoworkers were obtained from medical check-ups and company registers. Cross-sectional associations modeling the total effect from shift work (day shifts, shift work without nights, rotating shift work with nights, and night shifts) on hypertension were assessed. By sequential adjustments, the influence of behavioral, psychosocial, and physiological factors on the total effect was examined, with subsequent mediation and moderation analyses. Adjusted for confounders, shift work without nights (vs. day shifts) was significantly associated with hypertension (OR 1.15, 95%CI 1.02-1.30). The total effect was mediated by BMI, physical inactivity, and sleep disorders. No moderation of the total effect by behaviors was found. The association between shift work and hypertension seems mainly attributable to behavioral mechanisms.

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Citations

May 25, 2016·Current Biology : CB·Till Roenneberg, Martha Merrow
Jul 3, 2016·International Archives of Occupational and Environmental Health·BongKyoo ChoiMarnie Dobson
Apr 10, 2016·Occupational Medicine·J OhlanderK Radon
Apr 1, 2017·Korean journal of family medicine·Kyoung Hwa YuSo Yeon Ji
Jan 13, 2018·International Archives of Occupational and Environmental Health·Akiomi InoueAkizumi Tsutsumi
Oct 5, 2019·Journal of the American Heart Association·Barbara RiegelAlexandra L Hanlon
May 29, 2018·Current Urology Reports·Nanfu DengLarry I Lipshultz
Mar 1, 2019·International Archives of Occupational and Environmental Health·Johan OhlanderKatja Radon
Jan 16, 2021·International Journal of Molecular Sciences·Andy W C ManNing Xia
Feb 23, 2021·Hypertension·Nour MakaremMarwah Abdalla
Jul 3, 2021·International Journal of Environmental Research and Public Health·Sara Gamboa MadeiraDaniel Caldeira

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