PMID: 3382145Jan 1, 1988

Shiley INFUSAID Pump technology

Annals of the New York Academy of Sciences
J JohnstonJ Sluetz

Abstract

Totally implantable drug delivery devices have been shown to be safe and effective in the delivery of drugs both systemically and regionally. Applications have been developed for continuous infusions of drugs and are currently being developed for variable flow rates with more sophisticated programmable pumps. Some of the potential benefits of such devices include improved drug efficacy with reduced systemic toxicities, more controlled dosing of drugs, improved quality of life, delivery of proteins and peptides, and individualized patient dosing. The potential exists for creating biofeedback closed loop therapies for diabetes, cardiovascular diseases, and some central nervous system diseases in the future.

Citations

Jun 1, 1995·Annals of Neurology·J C Garcia-Monco, J L Benach
Nov 1, 1995·Journal of Neuro-oncology·S Bakhshi, R B North
Dec 1, 1995·Neurosurgery·K A WalterH Brem
Oct 5, 2015·Journal of Clinical Anesthesia·Robert N PilonSukumar P Desai
Jun 23, 2012·International Journal of Pharmaceutics·Daniela AllhennAlf Lamprecht
Jan 20, 2012·The Korean Journal of Pain·Seok Myeon RheeFrancis Sahngun Nahm
Aug 1, 1992·Developmental Medicine and Child Neurology·R W ArmstrongS Kube

Related Concepts

Catheterization
Medical Device Design
Intravenous Drug Delivery Systems
Computer Programs and Programming
Spinal Cord
Medical Laboratory Science

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