Shine-Through in PET/MR Imaging: Effects of the Magnetic Field on Positron Range and Subsequent Image Artifacts

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
Armin KolbMagdalena Rafecas

Abstract

Simultaneous PET/MR imaging is an emerging hybrid modality for clinical and preclinical imaging. The static magnetic field of the MR imaging device affects the trajectory of the positrons emitted by the PET radioisotopes. This effect translates into an improvement of the spatial resolution in transaxial images. However, because of the elongation of the positron range distribution along the magnetic field, the axial resolution worsens and shine-through artifacts may appear. These artifacts can lead to misinterpretation and overstaging. The aim of this work was to study the relevance of this effect. Measurements were performed in a 3-tesla PET/MR scanner. A 1-cm(2) piece of paper, soaked with a radioisotope and placed in air, was scanned, and the magnitude of the shine-through was quantified from the PET images for various radioisotopes. Additionally, PET/MR and PET/CT images of the lungs and the larynx with trachea of a deceased swine were obtained after injecting a mixture of NiSO4 and (68)Ga to simulate hot tumor lesions. For the radioactive paper, shine-through artifacts appeared in the location of the acrylic glass backplane, located 3 cm from the source in the axial direction. The ratio between the activity of the shine-thr...Continue Reading

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Citations

Jun 9, 2016·EJNMMI Physics·Maurizio Conti, Lars Eriksson
Jun 7, 2017·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Brian J LeeCraig S Levin
Jan 21, 2018·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Jacobo Cal-GonzalezJosé Manuel Udías
Jan 18, 2019·Physics in Medicine and Biology·C ParlB J Pichler
Apr 3, 2020·The British Journal of Radiology·Nicholas R EvansJames Hf Rudd
Oct 13, 2020·Frontiers in Physiology·Paulo R R V CaribéMichel Koole
Nov 22, 2020·Scientific Reports·Yaser H GholamiZdenka Kuncic
Apr 11, 2015·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Osman Ratib

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