Shockingly: the loss of Lyn leads to leakiness.

Blood
Seth J Corey, Regina M Day

Abstract

In this issue of Blood, Han et al demonstrate that endotoxin-induced mortality in a murine model of acute lung injury (ALI) was associated with increased vascular permeability attributable to loss of the Src family kinase (SFK) Lyn.

References

May 23, 1998·The Journal of Experimental Medicine·H NishizumiT Yamamoto
May 8, 2002·Nature Reviews. Molecular Cell Biology·Margaret C FrameJohn A Wyke
Jun 30, 2007·American Journal of Respiratory and Critical Care Medicine·Anne BergeronPhilippe Rousselot
Aug 30, 2013·The New England Journal of Medicine·Derek C Angus, Tom van der Poll

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