Short- and long-term effects of pulmonary rehabilitation for idiopathic pulmonary fibrosis: a systematic review and meta-analysis

Clinical Rehabilitation
Li ChengWei Jiang

Abstract

To investigate the short- and long-term effects of pulmonary rehabilitation in patients with idiopathic pulmonary fibrosis (IPF). An electronic search of MEDLINE, Embase and Cochrane Central databases along with hand search of relevant papers were performed on 15 March 2018. This study was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We searched the literature for randomized controlled trials of pulmonary rehabilitation in IPF patients. The outcomes were exercise capacity and health-related quality of life. Two authors independently extracted data, assessed trial eligibility and risk of bias. Meta-analyses were performed using RevMan and STATA software. We extracted data from four randomized controlled trials (142 participants). At short-term follow-up, pulmonary rehabilitation significantly enhanced 6-minute walk distance (6-MWD; weighted mean difference (WMD) = 38.38, 95% confidence interval (CI) = 4.64-72.12, I2 = 60.7%; P < 0.05), reduced St. George's Respiratory Questionnaire (SGRQ)/IPF-specific SGRQ (SGRQ-I) total score (WMD = -8.40, 95% CI = -11.44 to -5.36, I2 = 0%; P < 0.00001). At long-term follow-up, pulmonary rehabilitation could not enhance...Continue Reading

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Citations

Mar 15, 2019·Respirology : Official Journal of the Asian Pacific Society of Respirology·Thierry TroostersHeleen Demeyer
Jun 11, 2019·Expert Review of Respiratory Medicine·Onofre Moran-MendozaIngrid Harle
Jul 24, 2020·Current Opinion in Pulmonary Medicine·Katerina AntoniouJeffrey J Swigris
Sep 6, 2019·European Respiratory Review : an Official Journal of the European Respiratory Society·Vivien SomogyiMichael Kreuter
Nov 10, 2020·Respirology : Official Journal of the Asian Pacific Society of Respirology·Miao ZhouJiansheng Li
May 2, 2021·Archives of Physical Medicine and Rehabilitation·Sara Reina-GutiérrezDiana P Pozuelo-Carrascosa
Aug 20, 2020·Respiration; International Review of Thoracic Diseases·Andreas Rembert KoczullaMichael Kreuter

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Software Mentioned

STATA
RevMan

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