Short- and long-term outcomes after colorectal anastomotic leakage is affected by surgical approach at reoperation

International Journal of Colorectal Disease
Jens Ravn EriksenIsmail Gögenur

Abstract

Anastomotic leakage is the most serious surgical complication following colorectal resection, and surgical intervention is often required. The purpose of the study was to investigate short- and long-term outcomes after reoperation for anastomotic leakage. Patients with a symptomatic anastomotic leakage following a laparoscopic colorectal cancer resection from January 2009 to December 2014 were identified from our local prospective database. Patients were grouped according to the management of anastomotic leaks: local, lap, or open approach. Primary outcomes were length of stay, chance of bowel continuity, and overall mortality. A total of 113 patients were included. The median follow-up time was 40 months (0-82 months). Overall mortality was significantly associated with UICC stage III-VI disease (vs. UICC stage I-II disease) [adj. HR 5.35 (CI 2.32-12.4), p = 0.0001] and minimal invasive reoperation compared with open approach [local: adj. HR 0.12 (CI 0.03-0.52), p = 0.004; lap: adj. HR 0.32 (CI 0.12-0.86), p = 0.024]. Chance of bowel continuity was significantly increased in younger patients below 67 years [adj. OR 6.15 (1.76-21.5), p = 0.004] and following a local procedure [adj. OR 7.45 (1.07-51.8), p = 0.043]. Patients in t...Continue Reading

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Citations

Oct 30, 2020·International Journal of Colorectal Disease·UNKNOWN Italian ColoRectal Anastomotic Leakage (iCral) study groupMarco Catarci
May 1, 2021·Journal of Clinical Medicine·Constantine HalkiasSteven Wexner
Apr 13, 2021·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Lucia GraneroJosé Luis Hernández Lizoáin

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