Short-Bowel Syndrome: Epidemiology, Hospitalization Trends, In-Hospital Mortality, and Healthcare Utilization.

JPEN. Journal of Parenteral and Enteral Nutrition
Mohamed Tausif SiddiquiDonald F Kirby

Abstract

Short-bowel syndrome (SBS) is a common cause of chronic intestinal failure and is associated with increased morbidity, mortality, poor quality of life, and an increased burden on healthcare costs. We used the US Nationwide Inpatient Sample database from 2005 to 2014. We identified adult SBS hospitalizations by using a combination of International Classification of Diseases, Ninth Revision, Clinical Modification codes. We studied the demographics of the patients with SBS and analyzed the trends in the number of hospitalizations, in-hospital mortality, and healthcare costs. We also identified the risk factors associated with in-hospital mortality. A total of 53,040 SBS hospitalizations were identified. We found that SBS-related hospitalizations increased by 55% between 2005 (N = 4037) and 2014 (N = 6265). During this period, the in-hospital mortality decreased from 40 per 1000 to 29 per 1000 hospitalizations, resulting in an overall reduction of 27%. Higher mortality was noted in SBS patients with sepsis (6.7%), liver dysfunction (6.2%), severe malnutrition (6.0%), and metastatic cancer (5.4%). The overall mean length of stay (LOS) for SBS-related hospitalizations was 14.7 days, with a mean hospital cost of $34,130. We noted a st...Continue Reading

References

Jan 1, 1991·JPEN. Journal of Parenteral and Enteral Nutrition·P P Purdum, D F Kirby
Oct 1, 1970·The Surgical Clinics of North America·S J DudrickJ E Rhoads
Mar 1, 1993·JPEN. Journal of Parenteral and Enteral Nutrition·M A McFaddenD F Kirby
Nov 14, 1997·Gastroenterology·J A Vanderhoof, A N Langnas
Feb 7, 1998·Medical Care·A ElixhauserR M Coffey
Dec 24, 2002·Surgical and Radiologic Anatomy : SRA·G HounnouS Velut
Dec 4, 2003·Best Practice & Research. Clinical Gastroenterology·J SchalamonM E Höllwarth
Feb 20, 2004·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·I VantiniF Capra
Jul 6, 2004·The American Journal of Gastroenterology·John K DiBaiseJon A Vanderhoof
Aug 28, 2004·The American Journal of Gastroenterology·John K DiBaiseJon A Vanderhoof
Jun 28, 2005·Journal of the American College of Surgeons·Jon S ThompsonDebra L Sudan
Jan 25, 2006·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·John K DibaiseJon A Vanderhoof
Feb 14, 2006·Gastroenterology·Deirdre A Kelly
Apr 28, 2006·JPEN. Journal of Parenteral and Enteral Nutrition·Richard SalvinoEzra Steiger
Jul 14, 2006·Gut·J NightingaleUNKNOWN Small Bowel and Nutrition Committee of the British Society of Gastroenterology
Jul 26, 2006·The American Journal of Gastroenterology·Loris PironiMichael Staun
Jun 28, 2007·JPEN. Journal of Parenteral and Enteral Nutrition·Ezra Steiger
Apr 24, 2010·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Kristen M RhodaDonald F Kirby
Jun 23, 2010·Archives of Surgery·Abdullah ShatnaweiEzra Steiger
Nov 12, 2010·Gut·Loris PironiUNKNOWN Home Artificial Nutrition & Chronic Intestinal Failure Working Group of the European Society for Clinical Nutrition and Meta
Jul 6, 2011·Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association·Prasad Seetharam, Gabriel Rodrigues
Apr 14, 2012·Circulation Research·Brian J North, David A Sinclair
Sep 11, 2012·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Mira DreesenLudo Willems
Sep 21, 2012·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Aurelien AmiotFrancisca Joly
Sep 22, 2012·BMC Health Services Research·Efty StavrouSallie-Anne Pearson
Sep 26, 2012·JPEN. Journal of Parenteral and Enteral Nutrition·Donald F KirbyDorothy M Emery
Oct 16, 2012·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·Lisa L KirklandPrathibha Varkey
Oct 24, 2012·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Vanessa J Kumpf, Emma M Tillman
Apr 9, 2013·Journal of Gastroenterology·Kazuhiro WatanabeMamoru Watanabe
Nov 1, 2013·World Journal of Transplantation·Baris Dogu Yildiz
Nov 20, 2013·JPEN. Journal of Parenteral and Enteral Nutrition·Darlene G KellyMarion F Winkler
Dec 18, 2013·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Anirban Hom Choudhuri, Rajeev Uppal
Dec 19, 2013·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Olivia SaquiJohane P Allard
Jan 15, 2014·JPEN. Journal of Parenteral and Enteral Nutrition·Marion F Winkler, Carol E Smith
Feb 4, 2014·JPEN. Journal of Parenteral and Enteral Nutrition·Palle B Jeppesen
Mar 8, 2014·JPEN. Journal of Parenteral and Enteral Nutrition·Stanislaw KlekAleksander Galas
May 28, 2014·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Daniel RainesSaju Joseph
Jun 12, 2014·JPEN. Journal of Parenteral and Enteral Nutrition·Mira DreesenAndre Van Gossum
Dec 9, 2014·Current Opinion in Endocrinology, Diabetes, and Obesity·Palle B Jeppesen
May 15, 2015·JPEN. Journal of Parenteral and Enteral Nutrition·Marion F WinklerEzra Steiger
Nov 1, 2015·JPEN. Journal of Parenteral and Enteral Nutrition·Chaitanya PantRichard Gilroy

❮ Previous
Next ❯

Citations

Jun 24, 2021·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Marion F WinklerKishore Iyer
Oct 30, 2021·JPEN. Journal of Parenteral and Enteral Nutrition·Kishore R IyerJovana Lubarda

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved