Short communication: Association analysis of diacylglycerol acyltransferase (DGAT1) mutation on chromosome 14 for milk yield and composition traits, somatic cell score, and coagulation properties in Holstein bulls

Journal of Dairy Science
T BobboMartino Cassandro

Abstract

The aim of the present study was to determine the allele frequencies of the diacylglycerol acyltransferase (DGAT1) K232A mutation in Italian Holstein bulls and to estimate the effect of the mutation on milk yield, composition, somatic cell score, and coagulation traits (rennet coagulation time and curd firmness). For this purpose, 349 Italian Holstein bulls were genotyped for the DGAT1 mutation on chromosome 14. Association analysis was performed by regressing the number of copies for the K allele on the deregressed estimated breeding value of the individual. Breeding values were calculated using field data routinely collected in Northeast Italy. The frequencies of the AA, KA, and KK genotypes were 59.6, 32.1, and 8.3%, respectively, and the minor allele frequency (K variant) was 24.7%. The K allele was significantly associated with greater fat yield and fat, protein, and casein percentages and with reduced protein:fat ratio. The association between the DGAT1 mutation and somatic cell score was not significant, whereas a favorable association between presence of the K allele and milk coagulation properties was found. Results from the present study confirmed the effect of the diallelic DGAT1 polymorphism K232A on milk production...Continue Reading

References

Dec 1, 1987·Journal of Dairy Science·G R Wiggans, G E Shook
Dec 21, 2000·Journal of Colloid and Interface Science·C Lopez, E Dufour
Jan 7, 2003·Journal of Dairy Science·R J SpelmanR G Snell
Feb 26, 2004·Proceedings of the National Academy of Sciences of the United States of America·Bernard GrisartMichel Georges
Feb 9, 2006·Research in Veterinary Science·M V RipoliG Giovambattista
Jan 2, 2010·Genetics, Selection, Evolution : GSE·Dorian J GarrickRohan L Fernando
Apr 10, 2010·Animal Biotechnology·Marcos Vinicius G Barbosa da SilvaCurt P Van Tassell
Jul 1, 2008·Animal : an International Journal of Animal Bioscience·M SadeghiA Nejati Javaremi
Sep 25, 2012·The Journal of Dairy Research·Denis PrettoMartino Cassandro
Jul 6, 2015·Journal of Dairy Science·H BovenhuisJ A M van Arendonk
Nov 21, 2017·Journal of Dairy Science·Filippo MigliorChristine F Baes

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Citations

Dec 11, 2019·Animals : an Open Access Journal From MDPI·Mingxun LiYongjiang Mao
Jul 16, 2021·The Journal of Dairy Research·Xiaomei SunYongjiang Mao

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