Short communication: Meta-analysis on therapy of bovine endometritis with prostaglandin F2α -An update

Journal of Dairy Science
P HaimerlSebastian Arlt

Abstract

The objective of the study was to update a prior meta-analysis on the efficacy of the treatment of bovine endometritis with PGF2α. Clinical endometritis in cattle is defined as the presence of a purulent or mucopurulent vaginal discharge after 20 or 26 d, respectively, postpartum. Although the prevalence and impact of this disease are well known, the questions of whether and how to treat endometritis are still controversially discussed. Hence, to ensure timeliness of scientific results, we updated an existing meta-analysis published in 2013 that showed no treatment effect of PGF2α in cases of bovine endometritis. As in the prior meta-analysis, a comprehensive literature search was conducted. After applying specific inclusion and exclusion criteria, 3 trials remained that could be added to the 6 trials in the initial meta-analysis. Data for each trial were analyzed using the meta-analysis software Review Manager (version 5.3; The Nordic Cochrane Centre, Copenhagen, Denmark). Estimated effect sizes of PGF2α were calculated on calving to first service interval (CFSI) and calving to conception interval (CCI). As revealed by the initial meta-analysis, PGF2α treatment still had no effect on both reproductive parameters. Heterogeneity...Continue Reading

References

Sep 6, 2003·BMJ : British Medical Journal·Julian P T HigginsDouglas G Altman
Apr 16, 2005·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Raymond W Lam, Sidney H Kennedy
Oct 18, 2005·Theriogenology·I Martin SheldonRobert O Gilbert
Sep 19, 2009·Journal of Dairy Science·S ArltW Heuwieser
Oct 23, 2010·Journal of Dairy Science·J DubucS J LeBlanc
Mar 19, 2013·Journal of Dairy Science·P HaimerlS Arlt

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Citations

Aug 22, 2020·Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere·Lisa NeubrandMarc Drillich
Apr 29, 2021·Inflammation·Talha UmarGanzhen Deng

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