Short-course versus long-course antibiotic therapy for non-severe community-acquired pneumonia in children aged 2 months to 59 months

The Cochrane Database of Systematic Reviews
Batool A HaiderZulfiqar A Bhutta

Abstract

Pneumonia is the leading cause of mortality in children under five years of age. Treatment of pneumonia requires an effective antibiotic used in adequate doses for an appropriate duration. Recommended duration of treatment ranges between 7 and 14 days, but this is not based on any empirical evidence. Shorter duration of therapy, if found to be effective, could be particularly important in resource-poor settings where there is a high risk of death, poor access to medicines and health care, and limited budgets for medicines. To evaluate the efficacy of short-course versus long-course therapy with the same antibiotic for non-severe community-acquired pneumonia in children aged 2 to 59 months. We searched The Cochrane Central Register of Controlled Trials (CENTRAL); the Database of Abstracts of Reviews of Effects (DARE) (The Cochrane Library, 2007, Issue 3); MEDLINE (OVID) (January 1966 to September 2007); EMBASE (Embase.com) (1974 to September 2007); and LILACS (1982 to September 2007). All randomized controlled trials (RCTs) evaluating the efficacy of short-course versus long-course therapy using the same antibiotic for non-severe community-acquired pneumonia in children. Two review authors independently assessed trial quality an...Continue Reading

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Citations

Apr 26, 2012·The Pediatric Infectious Disease Journal·Rasa IzadnegahdarUNKNOWN Pneumonia Studies Group
Apr 28, 2009·Infectious Disease Clinics of North America·Petros I RafailidisMatthew E Falagas
May 27, 2014·The Cochrane Database of Systematic Reviews·Zohra S LassiZulfiqar A Bhutta
Jul 20, 2018·The Cochrane Database of Systematic Reviews·Rashmi R DasSushree S Naik
Apr 22, 2008·The Cochrane Database of Systematic Reviews·Batool A HaiderZulfiqar A Bhutta
Sep 7, 2018·The Cochrane Database of Systematic Reviews·Jesús López-AlcaldeManuel Gómez-García
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Jan 17, 2014·Archives of Disease in Childhood·Zohra S LassiZulfiqar A Bhutta
Jul 9, 2020·Frontiers in Pediatrics·Rim TannousPaul-Henri Torbey
Jan 21, 2021·The Cochrane Database of Systematic Reviews·Zohra S LassiZulfiqar A Bhutta
Apr 28, 2009·Infectious Disease Clinics of North America·Alexandros P GrammatikosMatthew E Falagas
Apr 11, 2012·Emergency Medicine Clinics of North America·Joseph Choi, Gary L Lee

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