PMID: 11915779Mar 28, 2002Paper

Short-term beta-hydroxy-beta-methylbutyrate supplementation does not reduce symptoms of eccentric muscle damage

International Journal of Sport Nutrition and Exercise Metabolism
D Paddon-JonesD Jenkins

Abstract

We examined the effects of short-term beta-hydroxy-beta-methylbutyrate (HMB) supplementation on symptoms of muscle damage following an acute bout of eccentric exercise. Non-resistance trained subjects were randomly assigned to a HMB supplement group (HMB, 40mg/kg bodyweight/day, n = 8) or placebo group (CON, n = 9). Supplementation commenced 6 days prior to a bout of 24 maximal isokinetic eccentric contractions of the elbow flexors and continued throughout post-testing. Muscle soreness, upper arm girth, and torque measures were assessed pre-exercise, 15 min post-exercise, and 1, 2, 3, 4, 7, and 10 days post-exercise. No pre-test differences between HMB and CON groups were identified, and both performed a similar amount of eccentric work during the main eccentric exercise bout (p > .05). HMB supplementation had no effect on swelling, muscle soreness, or torque following the damaging eccentric exercise bout (p > .05). Compared to a placebo condition, short-term supplementation with 40mg/kg bodyweight/day of HMB had no beneficial effect on a range of symptoms associated with eccentric muscle damage. If HMB can produce an ergogenic response, a longer preexercise supplementation period may be necessary.

Citations

Jan 15, 2010·Journal of Strength and Conditioning Research·David NunanKen A van Someren
Feb 5, 2013·Journal of the International Society of Sports Nutrition·Jacob M WilsonJose Antonio
Jul 12, 2005·Current Sports Medicine Reports·Tenley Palisin, Jason J Stacy
Feb 20, 2004·Journal of Sports Sciences·Ron J MaughanTrevor Lea
Mar 5, 2016·Journal of the International Society of Sports Nutrition·Minayuki ShiratoEisuke Ochi
Oct 24, 2018·Research in Sports Medicine·Yftach GepnerJay R Hoffman
May 21, 2008·Sports Medicine·Glyn Howatson, Ken A van Someren
Nov 28, 2013·Critical Reviews in Food Science and Nutrition·Feby LuckoseKolpe Radhakrishna
Aug 17, 2018·Medicine and Science in Sports and Exercise·Josephine S JakubowskiStuart M Phillips

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