Short-term cactus pear [Opuntia ficus-indica (L.) Mill] fruit supplementation ameliorates the inflammatory profile and is associated with improved antioxidant status among healthy humans

Food & Nutrition Research
Alessandro AttanzioMario Allegra

Abstract

Dietary ingredients and food components are major modifiable factors protecting immune system and preventing the progression of a low-grade chronic inflammation responsible for age-related diseases. Our study explored whether cactus pear (Opuntia ficus-indica, Surfarina cultivar) fruit supplementation modulates plasma inflammatory biomarkers in healthy adults. Correlations between inflammatory parameters and antioxidant status were also assessed in parallel. In a randomised, 2-period (2 weeks/period), crossover, controlled-feeding study, conducted in 28 healthy volunteers [mean age 39.96 (±9.15) years, BMI 23.1 (±1.5) kg/m2], the effects of a diet supplemented with cactus pear fruit pulp (200 g, twice a day) were compared with those of an equivalent diet with isocaloric fresh fruit substitution. With respect to control, cactus pear diet decreased ( p < 0.05) the pro-inflammatory markers such as tumour necrosis factor-α (TNF-α), interleukin (IL)-1β, interferon-γ (INF)-γ, IL-8, C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR), whereas it increased ( p < 0.05) the anti-inflammatory marker IL-10. Moreover, the diet decreased ratios between pro-inflammatory biomarkers (CRP, IL-6, IL-8, TNF-α) and anti-inflammatory b...Continue Reading

References

Nov 18, 2003·Arteriosclerosis, Thrombosis, and Vascular Biology·Cornelis Kluft, Moniek P M de Maat
Sep 28, 2004·The American Journal of Clinical Nutrition·Luisa TesoriereMaria A Livrea
Nov 13, 2004·Arteriosclerosis, Thrombosis, and Vascular Biology·Yuri IvashchenkoJan Torzewski
Feb 3, 2005·International Journal of Cardiology·Wolfgang Koenig
May 19, 2005·The Journal of Clinical Endocrinology and Metabolism·Sridevi DevarajIshwarlal Jialal
Apr 11, 2006·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Gordon A Zello
Sep 14, 2007·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Dora Il'yasovaMarco Pahor
Dec 29, 2007·The Journal of Pathology·C M Filippi, M G von Herrath
Sep 16, 2010·Free Radical Biology & Medicine·Simone ReuterBharat B Aggarwal
Oct 20, 2010·The British Journal of Nutrition·Javier González-GallegoMaría J Tuñón
Dec 1, 2010·Cytokine & Growth Factor Reviews·Robert SabatJens Geginat
Jul 5, 2013·Archives of Biochemistry and Biophysics·Susan T MayneWerner Gellermann
Dec 7, 2013·The Journal of Nutrition·Mario AllegraMaria Antonia Livrea
Oct 21, 2014·Endocrine, Metabolic & Immune Disorders Drug Targets·Marialaura BonaccioGiovanni de Gaetano
Aug 19, 2015·Archivum Immunologiae Et Therapiae Experimentalis·Aleksandra Wyczalkowska-TomasikLeszek Paczek
Jul 29, 2016·The American Journal of Clinical Nutrition·Zhi YuYing Bao
Aug 29, 2017·Journal of the Academy of Nutrition and Dietetics·Sarah Chang, Kristin Koegel

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