Short-term comparison of two non-surgical treatment modalities of peri-implantitis: Clinical and microbiological outcomes in a two-factorial randomized controlled trial.

Journal of Clinical Periodontology
Mauro MerliMichele Nieri

Abstract

To compare the efficacy of two different therapies (amino acid glycine abrasive powder and a desiccant material) and their combination in the non-surgical treatment of peri-implantitis. This was an examiner-blind randomized clinical trial, with 2-factorial design with a follow-up of 6 months. The combination of the two factors resulted in four interventions: (a) non-surgical debridement alone (C); (b) non-surgical debridement and a desiccant material (H); (c) non-surgical debridement and glycine powder (G); and (d) non-surgical debridement, desiccant material and glycine powder (HG). Sixty-four patients with peri-implantitis were randomized, 16 for each intervention. After six months, two implants failed in the G intervention. Mean pocket depth reduction was higher in patients treated with the desiccant material (estimated difference: 0.5 mm; 95% CI from 0.1 to 0.9 mm, p = .0229) while there was no difference in the patients treated with glycine powder (estimated difference: 0.1 mm; 95% CI from -0.3 to 0.5 mm, p = .7333). VAS for pain during intervention and VAS for pain after one week were higher for patients treated with glycine powder (p = .0056 and p = .0339, respectively). The success criteria and other variables did not r...Continue Reading

References

Aug 1, 1997·Community Dentistry and Oral Epidemiology·G D Slade
Nov 25, 2003·BMC Medical Research Methodology·Alan A MontgomeryPaul Little
Mar 30, 2010·Journal of Clinical Epidemiology·David MoherUNKNOWN Consolidated Standards of Reporting Trials Group
Nov 26, 2010·Journal of Clinical Periodontology·Stefan RenvertG Rutger Persson
Jan 24, 2012·Occupational and Environmental Medicine·G J de GroeneJ H Verbeek
Oct 25, 2012·Clinical Oral Implants Research·Manoj MuthukuruThomas F Flemmig
Mar 16, 2013·Journal of Clinical Periodontology·Stefan Listl, Stephen Birch
Jul 26, 2013·European Journal of Orthodontics·Nikolaos PandisTheodore Eliades
Jul 22, 2014·Journal of Clinical Periodontology·Mauro MerliMichele Nieri
Aug 16, 2014·Periodontology 2000·Elena FigueroMariano Sanz
Apr 14, 2015·Journal of Clinical Periodontology·Stefan ListlClovis M Faggion
Sep 13, 2015·Journal of Clinical Periodontology·Frank SchwarzStefan Renvert
Apr 23, 2016·The International Journal of Periodontics & Restorative Dentistry·Giovanpaolo Pini-PratoRoberto Rotundo
Jun 24, 2016·Clinical Oral Implants Research·Lisa J A Heitz-MayfieldNiklaus P Lang
May 28, 2019·Clinical Oral Investigations·José NartAlberto Monje
Sep 19, 2019·The International Journal of Oral & Maxillofacial Implants·Antonio LiñaresJuan Blanco

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.