Short-term complications of intravitreal injection of triamcinolone acetonide

Retina
Daniel B RothStuart N Green

Abstract

To describe the short-term complications associated with intravitreal triamcinolone acetonide (IVTA) injection in the treatment of posterior segment disorders. The medical records of 784 patients (929 consecutive eyes) were retrospectively reviewed at a single institution. One or more IVTA injections for treatment of a variety of steroid-responsive posterior segment disorders (predominantly diabetic macular edema, choroidal neovascularization, and retinal venous occlusions) were administered. Adverse events occurring within 3 months of the initial injection were identified. The most common adverse event occurring within 3 months after the initial injection was steroid-related ocular hypertension, with intraocular pressure spikes of >21 mm Hg in 21% of eyes and >25 mm Hg in 11% of eyes. Ocular inflammation occurred in six eyes (0.6%): four eyes with sterile hypopyon and two eyes without hypopyon. Three eyes (0.3%) had corneal epithelial defects thought to be related to pretreatment with povidone-iodine solution. No eyes had culture-positive infectious endophthalmitis. Cataract progression was not assessed in this analysis. IVTA injection for the treatment of steroid-responsive disorders of the posterior segment, when administere...Continue Reading

References

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Citations

Feb 4, 2009·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Yoko Miura, Johann Roider
Jul 24, 2012·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Seong Joon AhnHum Chung
Dec 19, 2008·Retina·Vinit B MahajanH Culver Boldt
Mar 17, 2015·Translational Vision Science & Technology·Juan-Carlos Gutiérrez-HernándezMark Humayun
Jun 19, 2013·Survey of Ophthalmology·Weerawat KiddeeYvonne M Buys
Jan 15, 2011·Acta Ophthalmologica·Sakiko Nakano GotoHidetoshi Yamashita
Sep 23, 2016·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Munish SharmaHeather Gappa-Fahlenkamp
Sep 10, 2015·The Cochrane Database of Systematic Reviews·Dina GewailyPaul B Greenberg
Dec 16, 2018·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Angeline Julius, Waheeta Hopper

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