Short-term digestive tolerance of different doses of NUTRIOSE FB, a food dextrin, in adult men

European Journal of Clinical Nutrition
E G H M van den HeuvelA F M Kardinaal

Abstract

To determine the tolerance of increasing dosages of an incompletely hydrolysed and/or incompletely absorbed food dextrin coming from wheat starch, NUTRIOSE FB, at daily levels of 10 and 15 g up to 60 and 80 g, respectively. A randomized, double-blind, multiple dose, placebo-controlled, combined crossover and parallel trial. The metabolic ward of TNO Nutrition and Food Research. A total of 20 healthy men (age 31.7 +/- 9.1 y; BMI 24.5 +/- 2.9 kg/m2). One group of 10 subjects consumed on top of their diet 10, 30 and 60 g of NUTRIOSE FB or maltodextrin (placebo) daily. The other group of 10 subjects consumed 15, 45 and 80 g daily. Each dose was consumed for 7 days. Compared with placebo, flatulence occurred more frequently over the last 6 days on 30, 60 or 80 g/day of NUTRIOSE FB (P < 0.05). During the last 24 h, that is, days 6-7, of 60 and 80 g/day of NUTRIOSE FB, the frequency of flatulence was even higher (P < 0.05). During the last 24 h on a daily dose of 60 g NUTRIOSE FB, the frequency of defecation decreased (P < 0.05). Bloating occurred more often during the last 24 h on 80 g/day of NUTRIOSE FB (P < 0.05). None of the doses of NUTRIOSE FB resulted in diarrhoea. Compared to baseline levels, breath H2 excretion, which was onl...Continue Reading

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Citations

Apr 2, 2008·The British Journal of Nutrition·Pascale RozanMarie-Hélène Saniez
Feb 17, 2006·European Journal of Clinical Nutrition·W PasmanA Kardinaal
Aug 25, 2007·European Journal of Clinical Nutrition·A GrysmanT M S Wolever
Jun 24, 2011·Journal of the American College of Nutrition·Julie-Anne NazareMartine Laville
Feb 24, 2009·Critical Reviews in Food Science and Nutrition·Hollie A Grabitske, Joanne L Slavin
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Jan 22, 2010·Annals of Nutrition & Metabolism·Maria L StewartJoanne L Slavin
Sep 26, 2013·Journal of Nutritional Science and Vitaminology·Yuka KishimotoShukuko Ebihara
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Dec 18, 2010·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Shuguang LiLarry E Miller
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May 20, 2011·International Journal of Food Sciences and Nutrition·Laetitia Guerin-DeremauxLarry E Miller
Nov 26, 2019·Journal of the American Association of Nurse Practitioners·Johnson W McRorieWilliam D Chey
May 30, 2020·Nutrition & Metabolism·Fan HuHongmei Zhang

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