Abstract
To evaluate the therapeutic effect of botulinum toxin A (BTX-A) injection on spastic gastrocnemius (GCM) and tibialis posterior muscles (TPo) by using the foot pressure measurement system (FPMS). Eighteen ambulatory CP patients were recruited in this study. BTX-A was injected into the GCM at a dose of 6-12 units/kg and TPo at a dose of 4-9 units/kg according to the severity of equinus and varus deformity. Foot contact pattern, pressure time integral (PTI), coronal index using the FPMS and Modified Ashworth Scale (MAS), and visual inspection of gait pattern were used for evaluation of the therapeutic effect of BTX-A injection. Clinical and FPMS data were statistically analyzed according to the muscle group. A significant decrease in the MAS score of the GCM and TPo was observed, and spastic equinovarus pattern during gait showed improvement after injection. The GCM+TPo injection group showed a significant decrease in forefoot, lateral forefoot pad, and lateral column PTI, and a significant increase in hindfoot PTI and coronal index. In the GCM only injection group, forefoot PTI and lateral column PTI were significantly decreased and hindfoot PTI was significantly increased. The TPo only injection group showed a significant decre...Continue Reading
References
Dec 1, 1990·Foot & Ankle·G B Holmes, L Timmerman
Aug 26, 1998·The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons·D G ArmstrongL A Lavery
Sep 2, 1999·Gait & Posture·D H SutherlandS J Mubarak
Dec 5, 2000·Foot & Ankle International·D MetaxiotisL Doederlein
Jan 13, 2001·Gait & Posture·D J OeffingerC M Tylkowski
Feb 15, 2001·Journal of Pediatric Orthopedics·J S DavittP F Armstrong
Feb 15, 2001·Journal of Pediatric Orthopedics·F J Liggio, R Kruse
Apr 18, 2001·Developmental Medicine and Child Neurology·A M BakheitS H Rousso
Mar 29, 2003·Diabetes Care·Lawrence A LaveryAndrew J M Boulton
Jun 3, 2004·The Journal of Bone and Joint Surgery. American Volume·Harry Huber, Michel Dutoit
Jan 13, 2005·JAMA : the Journal of the American Medical Association·Nalini SinghBenjamin A Lipsky
Jun 7, 2005·Developmental Medicine and Child Neurology·M FalsoP Manganotti
Apr 26, 2006·Archives of Physical Medicine and Rehabilitation·Eun Sook ParkChan Woo Park
Sep 27, 2006·Journal of Pediatric Orthopedics. Part B·Michael J OddyDeborah M Eastwood
Nov 1, 2007·Journal of Children's Orthopaedics·Jacques RiadFreeman Miller
Jan 28, 2010·Journal of Pediatric Orthopedics·Chester M TylkowskiDonna J Oeffinger
Jun 18, 2010·Clinical Rehabilitation·Yun Hyung Koog, Byung-Ii Min
Aug 25, 2011·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Antigone S PapavasiliouConstantine Filiopoulos
Apr 17, 2012·Annals of Rehabilitation Medicine·Sook Joung LeeJu Seok Ryu
May 15, 2012·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Hristina ColovicDragana Radovic-Janosevic
Jan 25, 2013·Toxins·Marc DegelaenBernard Dan
Jun 13, 2013·Neurorehabilitation and Neural Repair·Benjamin BollensThierry Deltombe
Jul 16, 2013·Archives of Physical Medicine and Rehabilitation·Ettie Ben-ShabatAnne E Holland
Mar 25, 2014·Annals of Physical and Rehabilitation Medicine·C BoulayE Viehweger