PMID: 8970869Jan 1, 1995Paper

Short-term effect of dipyridamole on blood flow velocities in the extraocular vessels

International Ophthalmology
H J KaiserJ Flammer

Abstract

Dipyridamole is known to inhibit platelet aggregation and to induce vasodilatation. It has been shown that dipyridamole increases blood flow in various tissues in humans as well as in the eyes of animals. We studied the influence of dipyridamole in a prospective open trial in 23 patients with impaired ocular circulation due to different causes, based on experienced clinical judgement, such as anterior ischemic optic neuropathy, vasospastic syndrome, glaucoma, or central retinal vein occlusion. Blood flow velocities in the ophthalmic artery, central retinal artery and vein, one lateral and one medical posterior ciliary artery were measured using a Siemens Quantum 2000 color Doppler device. Blood flow velocities were measured before and under treatment. Dipyridamole increased blood flow velocities significantly in all vessels measured. Therefore, it seems promising to evaluate the effect of dipyridamole over a longer period in patients with impaired ocular blood flow.

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Citations

Jan 15, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Chantal VulstekeThierry Zeyen
Oct 24, 2007·International Ophthalmology·Fernando GalassiUgo Menchini
Apr 30, 2003·American Journal of Ophthalmology·Mücahit SatilmisJosef Flammer
Oct 8, 1999·American Journal of Ophthalmology·B SennJ Flammer
Mar 10, 2001·Ophthalmology·J KountourasC Zavos
Apr 5, 2001·Progress in Retinal and Eye Research·J FlammerT Resink
Aug 2, 2002·Progress in Retinal and Eye Research·Josef FlammerEinar Stefánsson
Oct 25, 2003·Progress in Retinal and Eye Research·Vital P CostaLuis Metzner Serra
Jan 27, 2005·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Oliver ArendBernard Schwartz
Nov 1, 2007·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Fernando GalassiUgo Menchini
Dec 24, 2015·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Moshe RogosnitzkyY Robert Barishak
Dec 6, 2007·Survey of Ophthalmology·Maneli Mozaffarieh, Josef Flammer
Jun 8, 2013·The EPMA Journal·Josef FlammerAndreas J Flammer
Jul 21, 2017·The EPMA Journal·Josef Flammer, Katarzyna Konieczka

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