Short-term fluctuations in personal black carbon exposure are associated with rapid changes in carotid arterial stiffening

Environment International
Eline ProvostTim Nawrot

Abstract

Vascular changes may underpin the association between airborne black carbon (BC) and cardiovascular events. Accurate assessment of personal exposure is a major challenge in epidemiological research. BC concentrations are strongly related to time-activity patterns, which is particularly relevant when investigating short-term effects. We investigated associations between arterial stiffness and personal short-term BC exposure. This panel study included 54 healthy adults (92% women, mean age 40.7years). BC exposure was monitored individually with a micro-aethalometer during one workweek. Functional and structural properties of the carotid artery were examined ultrasonographically on two separate days. The effect of different short-term personal BC exposure windows (1, 2, 4, 6, 8, 24 and 48h before the ultrasound examination) on carotid artery stiffness was estimated using mixed models while adjusting for other known correlates of arterial stiffness. Median personal BC exposures within the same day ranged from 599.8 to 728.9ng/m(3) and were associated with carotid arterial stiffness measures. Young's elastic modulus and pulse wave velocity, both measures of stiffness, were positively associated with BC exposure, while the distensibi...Continue Reading

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Citations

Jul 1, 2016·Current Environmental Health Reports·Dries S Martens, Tim S Nawrot
Nov 21, 2018·Environmental Health : a Global Access Science Source·Hans ScheersLidia Casas
Mar 7, 2019·International Journal of Environmental Research and Public Health·Hanns MoshammerStefanie Peter
Feb 24, 2021·Environmental Pollution·Admir Créso TarginoDavid Andrés Monroy
Aug 17, 2021·Toxicology and Industrial Health·Nina L StuteStephen M Ratchford

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