Abstract
Infection of total knee arthroplasty (TKA) is a rare but devastating complication. Two-stage revision is an effective treatment for late infected TKA. This study aimed to assess the short-term results of two-stage revision using articulating antibiotic-loaded spacers. Twenty-five patients (10 men and 15 women) were diagnosed with late infections after TKA and treated with two-stage revision from April 2006 to August 2010; 19 of these patients had TKA for osteoarthritis and 6 for rheumatoid arthritis. Median age was 64.9 (range, 56-83) years. In the first-stage surgery, the prosthesis and all bone cement was removed. After thorough debridement, bone cement with vancomycin and tobramycin was put into a die cavity and made into temporary femoral and tibial spacers, respectively. In the cases of good knee range of motion, the temporary spacers were affixed to the bone surface using the same antibiotic bone cement. In the second surgery, gentamycin Refobacin Bone Cement with vancomycin was used to fix the prosthesis. After two-stage revision, patients were followed up clinically and radiologically at 1, 3, and 6 months, and then annually. Knee Society Score (KSS), knee function score, knee pain score, and knee range of motion (ROM) ...Continue Reading
References
Jan 1, 1997·The American Journal of Sports Medicine·K D Shelbourne, R V Trumper
May 30, 1998·JAMA : the Journal of the American Medical Association·W ZimmerliP E Ochsner
Nov 5, 1998·The Journal of Arthroplasty·D A DennisK N Dennis
Aug 2, 2001·Acta Orthopaedica Scandinavica·A González Della ValleE A Salvati
Dec 6, 2001·The Journal of Antimicrobial Chemotherapy·C BetriuJ J Picazo
Nov 20, 2002·Clinical Orthopaedics and Related Research·Roger H EmersonLinda L Higgins
Jan 24, 2003·The Journal of Bone and Joint Surgery. American Volume·Dean T TsukayamaRichard Kyle
Oct 18, 2003·The Journal of Bone and Joint Surgery. American Volume·R M Dominic MeekClive P Duncan
Dec 4, 2004·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Konstantinos AnagnostakosWerner Jung
Aug 2, 2005·Clinical Orthopaedics and Related Research·J William Costerton
Nov 3, 2007·Clinical Orthopaedics and Related Research·R Stephen J BurnettRobert L Barrack
Jan 31, 2009·International Journal of Antimicrobial Agents·K TotéP Cos
May 29, 2009·The Journal of the American Academy of Orthopaedic Surgeons·Cale JacobsMichael E Berend
Aug 12, 2009·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Dario RegisPietro Bartolozzi
Nov 3, 2010·Clinical Orthopaedics and Related Research·Geoffrey S Van ThielCraig J Della Valle
Sep 3, 2011·Acta Orthopaedica·En-Rung ChiangWei-Ming Chen
Nov 3, 2011·Clinical Orthopaedics and Related Research·Giles R ScuderiW N Scott
Dec 7, 2011·Indian Journal of Orthopaedics·Parag GargSamar K Gupta
May 25, 2012·Arthritis Care & Research·Natalie J CollinsEwa M Roos
Jul 20, 2012·The Journal of Bone and Joint Surgery. American Volume·Javad ParviziAlan Seth Greenwald
May 3, 2013·The Journal of Bone and Joint Surgery. American Volume·Robert S NambaElizabeth W Paxton
Jul 31, 2013·The Journal of Arthroplasty·Jason S PruzanskyCalin S Moucha
Oct 2, 2014·Journal of Long-term Effects of Medical Implants·Antonia F Chen, Javad Parvizi
Oct 15, 2014·Antimicrobial Agents and Chemotherapy·R P HowlinP Stoodley
Aug 15, 2015·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Michael DrexlerDavid Backstein
May 21, 2016·The Journal of Knee Surgery·Eugenio VecchiniBruno Magnan
Jul 5, 2016·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Ewout S VeltmanRudolf W Poolman
Citations
Mar 12, 2020·Orthopaedic Surgery·Jing-Yu ZhangXiu-Chun Yu
Feb 23, 2020·The Journal of Bone and Joint Surgery. American Volume·Cindy R NahhasCraig J Della Valle
May 8, 2020·The Journal of Bone and Joint Surgery. American Volume·Cindy R NahhasCraig J Della Valle
Feb 6, 2021·Journal of Orthopaedic Surgery and Research·Hui SunXiangbei Qi
Apr 4, 2021·Journal of Clinical Medicine·Kristoff HammerichJoerg Mika
Nov 5, 2021·Orthopaedic Surgery·Li-Hong WangGuo-Hong Xu