Short-term outcomes after liver resection for malignant and benign disease in the age of ERAS

HPB : the Official Journal of the International Hepato Pancreato Biliary Association
Michael J HughesStephen Wigmore

Abstract

Enhanced Recovery After Surgery protocols have been implemented effectively after liver resection and provide benefits in terms of general morbidity rates. In order to optimise peri-operative care protocols and minimise morbidity, further investigation is required to identify factors associated with poor outcome after liver resection. A retrospective analysis of patients undergoing liver resection and enhanced recovery care between January 2006 and September 2012 was conducted. Data were collected on patient outcome and demographics, operative and pathological details. Univariate and multivariate analyses were performed to determine independent predictors of adverse outcome. 603 patients underwent liver resection during the study period. Morbidity and mortality rates were 34.3% and 1.5% respectively. The only predictor of major morbidity was extended resection (OR 4.079; 95% CI 2.177-7.642). Extended resection is associated with major morbidity. When determining optimum peri-operative care, ERAS protocols must incorporate care components that can mitigate against morbidity associated with extended resection.

References

Nov 1, 2005·Journal of Hepato-biliary-pancreatic Surgery·Steven M Strasberg
Jun 5, 2007·Journal of the American College of Surgeons·Sophia ViraniKenneth K Tanabe
Jul 12, 2008·The British Journal of Surgery·R M van DamUNKNOWN Enhanced Recovery After Surgery (ERAS) Group
Jul 25, 2008·Annals of Surgery·Henrik Kehlet, Douglas W Wilmore
Jul 6, 2010·The British Journal of Surgery·P O HendryUNKNOWN Enhanced Recovery After Surgery (ERAS) Group
Aug 14, 2012·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Erica J RevieStephen J Wigmore
Feb 1, 2013·The British Journal of Surgery·M N MavrosT M Pawlik
Apr 9, 2013·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·C Y NiW P Zhou
Jun 12, 2013·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Vincent W T LamArthur J Richardson
Mar 26, 2014·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Michael J HughesStephen J Wigmore

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Citations

Aug 11, 2016·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Kim M C van MierloSteven W M Olde Damink
Feb 23, 2019·World Journal of Surgery·Michael J HughesRichard J E Skipworth
May 28, 2020·Annals of Hepato-biliary-pancreatic Surgery·Andrew K Y FungPaul B S Lai
May 15, 2016·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Haipeng MengLunan Yan
Nov 10, 2017·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Kotaro SugawaraNobutaka Tanaka
Oct 31, 2020·The American Surgeon·Jennifer A LeeLouis Andrew DiFronzo
Jan 23, 2021·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Arthur K E ElfrinkUNKNOWN Dutch Hepato Biliary Audit Group
Nov 19, 2018·Journal of Visceral Surgery·R BrustiaO Scatton
May 27, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Sanli JinDong Pang

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