Short-term outcomes of ablation therapy for hepatic tumors: evidence from the 2006-2009 nationwide inpatient sample

Annals of Surgical Oncology
Justin P FoxJames Ouellette

Abstract

Radiofrequency ablation (RFA) for the treatment of hepatic tumors has been increasingly used across the United States. Whether treatment-related morbidity has remained low with broader adoption is unclear. We conducted this study to describe in-hospital morbidity associated with RFA for hepatic tumors and to identify predictors of adverse events in a nationally representative database. Using the 2006-2009 Nationwide Inpatient Sample, we evaluated all patients aged ≥40 years who underwent an elective RFA for primary or metastatic liver tumors (N = 1298). Outcomes included in-hospital procedure-specific and postoperative complications. Multivariable logistic regression analyses were performed to identify patient and facility predictors of complications. Most patients underwent a percutaneous (39.9 %) or laparoscopic (22.0 %) procedure for metastatic liver tumors (57.5 %). Procedure-specific complications were frequent (18.2 %), with transfusion requirements (10.7 %), intraoperative bleeding (4.3 %), and hepatic failure (2.8 %) being the most common. Arrhythmias [adjusted odds ratio (AOR) = 1.93 (1.23-3.04)], coagulopathy [AOR = 4.65 (2.95-7.34)], and an open surgical approach [AOR = 2.77 (1.75-4.36)] were associated with an incre...Continue Reading

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Citations

Jan 8, 2016·Journal of Hepatology·Philip N OkaforJayant A Talwalkar
Nov 19, 2013·Techniques in Vascular and Interventional Radiology·Constantinos T SofocleousElena N Petre
Jan 29, 2014·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Rebecca M TuttleMinia Hellan
Dec 24, 2014·Journal of Vascular and Interventional Radiology : JVIR·Brian T WelchThomas D Atwell

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