Abstract
Radiofrequency ablation (RFA) for the treatment of hepatic tumors has been increasingly used across the United States. Whether treatment-related morbidity has remained low with broader adoption is unclear. We conducted this study to describe in-hospital morbidity associated with RFA for hepatic tumors and to identify predictors of adverse events in a nationally representative database. Using the 2006-2009 Nationwide Inpatient Sample, we evaluated all patients aged ≥40 years who underwent an elective RFA for primary or metastatic liver tumors (N = 1298). Outcomes included in-hospital procedure-specific and postoperative complications. Multivariable logistic regression analyses were performed to identify patient and facility predictors of complications. Most patients underwent a percutaneous (39.9 %) or laparoscopic (22.0 %) procedure for metastatic liver tumors (57.5 %). Procedure-specific complications were frequent (18.2 %), with transfusion requirements (10.7 %), intraoperative bleeding (4.3 %), and hepatic failure (2.8 %) being the most common. Arrhythmias [adjusted odds ratio (AOR) = 1.93 (1.23-3.04)], coagulopathy [AOR = 4.65 (2.95-7.34)], and an open surgical approach [AOR = 2.77 (1.75-4.36)] were associated with an incre...Continue Reading
References
Mar 11, 1999·The New England Journal of Medicine·H B El-Serag, A C Mason
Aug 10, 2000·Medical Care·A G LawthersL I Iezzoni
Apr 12, 2002·The New England Journal of Medicine·John D BirkmeyerDavid E Wennberg
Aug 21, 2002·Medical Care·Gregory S CooperJoan L Warren
Sep 26, 2002·The British Journal of Surgery·S MulierL Michel
Feb 8, 2003·Current Problems in Diagnostic Radiology·Teresa BerrocalManuel L Santamaría
Dec 3, 2003·The New England Journal of Medicine·John D BirkmeyerF Lee Lucas
Mar 17, 2004·Annals of Surgery·Steven A CurleyFrancesco Izzo
Jul 10, 2004·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·C SouvignetL Baril
Dec 22, 2007·Oncology·Hiroshi KasugaiUNKNOWN Osaka Liver Cancer Study Group
Feb 5, 2008·Gastroenterology·Gilaad G KaplanBruce E Sands
Mar 26, 2008·American Journal of Surgery·Sean GarreanN Joseph Espat
Sep 26, 2009·Annals of Surgery·Garth H UtterPatrick S Romano
Oct 21, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Sandra L WongAl B Benson
Mar 30, 2010·Journal of the American College of Surgeons·Nader N MassarwehDavid R Flum
Jun 12, 2010·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Kate C YoungCurtis G Benesch
Mar 23, 2011·The Surgical Clinics of North America·Jay Requarth
Apr 9, 2011·Journal of the American College of Surgeons·Ann M BorzeckiAmy K Rosen
Citations
Jan 8, 2016·Journal of Hepatology·Philip N OkaforJayant A Talwalkar
Nov 19, 2013·Techniques in Vascular and Interventional Radiology·Constantinos T SofocleousElena N Petre
Jan 29, 2014·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Rebecca M TuttleMinia Hellan
Dec 24, 2014·Journal of Vascular and Interventional Radiology : JVIR·Brian T WelchThomas D Atwell