Short-term Outcomes of Transanal Hemorrhoidal Dearterialization With Mucopexy Versus Vessel-Sealing Device Hemorrhoidectomy for Grade III to IV Hemorrhoids: A Prospective Randomized Multicenter Trial.

Diseases of the Colon and Rectum
L TrentiTHDLIGA-RCT Study Group

Abstract

Transanal hemorrhoidal dearterialization with mucopexy and vessel-sealing device hemorrhoidectomy seem to reduce postoperative pain compared with classic excisional hemorrhoidectomy, but whether one of them is superior remains unclear. We compared transanal hemorrhoidal dearterialization with mucopexy and vessel-sealing device hemorrhoidectomy. This was a multicenter, randomized controlled trial. The study was conducted at 6 Spanish centers. Patients aged ≥18 years with grade III to IV hemorrhoids were included. Patients were randomly assigned to transanal hemorrhoidal dearterialization with mucopexy (n = 39) or vessel-sealing device hemorrhoidectomy (n = 41). Primary outcome was the mean postoperative number of days in which patients needed nonsteroidal anti-inflammatory drugs. Secondary outcomes were postoperative pain, 30-day morbidity, patient satisfaction, Vaizey score, hemorrhoid symptoms score, return to work, and quality of life. More patients were still taking analgesia in the vessel-sealing device hemorrhoidectomy group during the second postoperative week compared with the transanal hemorrhoidal dearterialization with mucopexy group (87.8% vs 53.8%; p = 0.002). For the transanal hemorrhoidal dearterialization with mu...Continue Reading

References

Feb 1, 1990·Gastroenterology·J F Johanson, A Sonnenberg
May 2, 2000·Diseases of the Colon and Rectum·J Konsten, C G Baeten
Mar 25, 2010·BMJ : British Medical Journal·Kenneth F SchulzUNKNOWN CONSORT Group
Aug 10, 2011·Diseases of the Colon and Rectum·David E RivadeneiraUNKNOWN Standards Practice Task Force of The American Society of Colon and Rectal Surgeons
May 9, 2012·World Journal of Gastroenterology : WJG·Varut Lohsiriwat
Jun 1, 2012·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·N P RossA J M Watson
Jun 27, 2012·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·C RattoV De Simone
May 29, 2013·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·P I DenoyaR Bergamaschi
Sep 13, 2013·Techniques in Coloproctology·C Ratto
Dec 4, 2013·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Maia A QarabakiNodari G Giorgadze
Sep 4, 2014·The New England Journal of Medicine·Danny Jacobs

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Citations

Jun 1, 2020·International Journal of Colorectal Disease·Matteo Di GiuseppeFrancesco Mongelli
May 10, 2020·International Journal of Colorectal Disease·Gregoire LongchampFrédéric Ris
Jan 21, 2021·World Journal of Surgery·Kasun LakmalDharmabandhu N Samarasekera
Mar 5, 2020·The British Journal of Surgery
Jun 9, 2021·International Journal of Colorectal Disease·Bianca AibuedefeJuan Lucas Poggio
Aug 17, 2021·Journal of the Anus, Rectum and Colon·Akiharu KuriharaKimihiko Funahashi
Aug 22, 2021·International Journal of Colorectal Disease·Zutoia BalciscuetaNatalia Uribe
Jul 30, 2021·Diseases of the Colon and Rectum

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