PMID: 6658834Dec 1, 1983Paper

Short term toxicity study in rats dosed with peppermint oil

Toxicology Letters
I ThorupP Olsen


Peppermint oil was given p.o. to groups of 10 male and 10 female rats at dosage levels of 0, 10, 40 and 100 mg/kg bw/day respectively for 28 days. Histopathological changes in the white matter of the cerebellum especially were seen at dose levels of 40 and 100 mg/kg bw/day and consisted of cyst-like spaces scattered in the white matter. There were no obvious signs of clinical symptoms due to the encephalopathy.


Jan 11, 1976·Toxicology and Applied Pharmacology·G L KennedyJ C Calandra
Jul 1, 1965·Journal of Pharmaceutical Sciences·T H Eickholt, R H Box
Jul 1, 1961·Clinica Chimica Acta; International Journal of Clinical Chemistry·E van KAMPEN, W G ZIJLSTRA

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