Short-term weather variability in Chicago and hospitalizations for Kawasaki disease

Epidemiology
William CheckleyStanford T Shulman

Abstract

: Kawasaki disease exhibits a distinct seasonality, and short-term changes in weather may affect its occurrence. : To investigate the effects of weather variability on the occurrence of this syndrome, we conducted a time-between-events analysis of consecutive admissions for Kawasaki disease to a large pediatric hospital in Chicago. We used gamma regression to model the times between admissions. This is a novel application of gamma regression to model the time between admissions as a function of subject-specific covariates. : We recorded 723 admissions in the 18-year (1986-2003) study period, of which 700 had complete data for analysis. Admissions for Kawasaki disease in Chicago were seasonal: The mean time between admissions was 34% shorter (relative time = 0.66, 95% confidence interval 0.54-0.81) from January-March than from July-September. In 1998, we recorded a larger number of admissions for Kawasaki disease (n = 65) than in other years (mean n = 37). January-March months of 1998 were warmer by a mean of 3 degrees C (1.5 degrees C-4.4 degrees C) and the mean time between admissions was 48% shorter (relative time = 0.52, 0.36-0.75) than in equivalent periods of other study years. : Our findings show that atypical changes in ...Continue Reading

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Citations

Feb 24, 2011·The Pediatric Infectious Disease Journal·Maskit Bar-MeirMichael Dor
Feb 2, 2010·Pediatrics International : Official Journal of the Japan Pediatric Society·Yahui T LinBrian W McCrindle
Aug 9, 2016·The Journal of Pediatrics·Andrew S ZeftC Arden Pope
Feb 8, 2011·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·F J Caballero-MoraM Sánchez-Bayle
Feb 23, 2012·Scientific Reports·Xavier RodóJane C Burns
Nov 16, 2017·The Pediatric Infectious Disease Journal·Joseph Y AbramsYosikazu Nakamura

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