Short-time dental resin biostability and kinetics of enzymatic degradation

Acta Biomaterialia
Xiaohong WangJirun Sun

Abstract

Resin biostability is of critical importance to the durability of methacrylate-based dental resin restorations. Current methods for evaluating biostability take considerable time, from weeks to months, and provide no short-time kinetics of resin degradation. The objective of this study is to develop a more sensitive method to assess resin biostability over short-time spans (hours to days) that will enhance our understanding of biostability and its resin chemistry. Ultra-flat resin films of equimolar urethane dimethacrylate (UDMA) and triethylene glycol dimethacrylate (TEGDMA) are produced through photo-curing between two flat surfaces. Next, metal-covered enclaves and bare-resin channels are generated using stencil lithography to create both degradable and protected (internal reference) regions simultaneously in a single specimen. Resins having three different degrees of vinyl conversion (DC) are compared, and changes of surface roughness and step height in the two regions are monitored by atomic force microscopy (AFM) before and after incubated in enzyme solutions and saline controls. Specimen biostability is ranked based on the topological profile changes when viewed in cross-section before and after enzymatic challenges. In ...Continue Reading

References

Oct 1, 1990·Dental Materials : Official Publication of the Academy of Dental Materials·F A RueggebergC W Fairhurst
Sep 1, 1996·Journal of Oral Rehabilitation·R M GuerraP Ortiz
Aug 10, 1999·Journal of Dental Research·J P SanterreH Tsang
Sep 27, 2000·Journal of Dental Research·P SpencerJ R Swafford
May 10, 2001·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·J P SanterreB W Leung
May 7, 2002·Dental Materials : Official Publication of the Academy of Dental Materials·Pietro AusielloCarel L Davidson
Jul 13, 2002·Journal of Biomedical Materials Research·Masanori HashimotoMinoru Kubota
Feb 4, 2003·Journal of Dental Research·J De MunckG Vanherle
Oct 10, 2003·Journal of Biomaterials Science. Polymer Edition·Y Finer, J P Santerre
Dec 24, 2003·Journal of Dental Research·Y Finer, J P Santerre
Apr 2, 2004·Journal of Biomedical Materials Research. Part a·Y Finer, J P Santerre
Aug 10, 2005·Dental Materials : Official Publication of the Academy of Dental Materials·Jack L Ferracane
Nov 17, 2006·Journal of Biomedical Materials Research. Part a·Y Finer, J P Santerre
Apr 13, 1945·Science·C H Sawyer
Jun 25, 2008·Journal of Dental Research·P J KoinL Hanley
Aug 7, 2008·The Review of Scientific Instruments·J L WassermanN Marković
Dec 18, 2008·Journal of Applied Oral Science : Revista FOB·Ana Carolina ValinotiLucianne Cople Maia
Sep 19, 2009·Nanotechnology·O Vazquez-MenaJ Brugger
Mar 2, 2010·Dental Materials : Official Publication of the Academy of Dental Materials·Ana F BettencourtMatilde F Castro
Aug 19, 2010·Advanced Materials·Yifu DingSheng Lin-Gibson
Oct 20, 2010·Biomacromolecules·Jirun SunSheng Lin-Gibson
Aug 21, 2013·Dental Materials : Official Publication of the Academy of Dental Materials·Leo TjäderhaneDavid H Pashley
Sep 13, 2013·Journal of Dental Research·M BourbiaY Finer
Oct 12, 2013·Dental Materials : Official Publication of the Academy of Dental Materials·Yasaman DelavizJ Paul Santerre
Feb 22, 2014·Operative Dentistry·Gc PadovaniRm Puppin-Rontani
Jun 22, 2014·Dental Materials : Official Publication of the Academy of Dental Materials·Kuihua CaiJ Paul Santerre
Sep 29, 2015·Chemical Communications : Chem Comm·J HermannsdörferA Verch

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Citations

Jul 23, 2019·Journal of Dental Research·S FrukhtbeynJ Sun
Nov 11, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Eliseu A MünchowMarco C Bottino

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