Shortcut to success? Negotiating genetic uniqueness in global biomedicine

Social Studies of Science
Heta Tarkkala, Aaro Tupasela

Abstract

Since the sequencing of the human genome, as well as the completion of the first Human Genome Diversity Project, the benefits of studying one human population over another has been an ongoing debate relating to the replicability of findings in other populations. The leveraging of specific populations into research markets has made headlines in cases such as deCode in Iceland, Quebec Founder Population, and Generation Scotland. In such cases, researchers and policy makers have used the genetic and historical uniqueness of their populations to attract scientific, commercial and political interest. In this article, we explore how in countries with population isolates, such as Finland, the researchers balance considerations relating to the generalization and replicability of findings in small yet unique research populations to global biomedical research interests. This highlights challenges related to forms of competition associated with genetics research markets, as well as what counts as the 'right' population for genetic research.

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Citations

Oct 6, 2018·Social Studies of Science·Elise K Burton
Jun 2, 2020·Frontiers in Genetics·Justin ReedyErika Blacksher
May 28, 2019·Life Sciences, Society and Policy·Karoliina Snell, Heta Tarkkala
May 7, 2019·Social Studies of Science·Alison Cool
Jun 22, 2021·Public Understanding of Science·Karoliina Snell, Heta Tarkkala
Dec 31, 2021·Health·Karoliina SnellAaro Tupasela

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Methods Mentioned

BETA
Human Genome Sequencing

Software Mentioned

DeCode
FinnGen
SITRA

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