PMID: 8606285Mar 1, 1996Paper

Shortened Doppler-derived mitral A wave deceleration time: an important predictor of elevated left ventricular filling pressure

Journal of the American College of Cardiology
A TenenbaumZ Vered

Abstract

The aim of this study was to investigate whether a new variable of mitral inflow, A wave deceleration time, identifies patients with elevated left ventricular filling pressures. In patients with an elevated left ventricular end-diastolic pressure, the increase in left ventricular pressure after atrial contraction rapidly exceeds left atrial pressure, resulting in abrupt cessation of the A wave. Therefore, we postulated that a shortening of A wave deceleration time might be a marker for elevated end-diastolic pressure. Adequate pulsed Doppler mitral inflow velocities could be recorded in 40 of 44 consecutive patients undergoing cardiac catheterization with capillary wedge pressure in 20 patients, and within 1 h after left ventricular end-diastolic pressure recording in 20. Fifteen healthy volunteers were also studied. Left ventricular end-diastolic pressure was 8 to 35 mm Hg, and mean pulmonary wedge pressure was 6 to 37 mm Hg. Close correlations were found between A wave deceleration time and mean pulmonary wedge pressure (r = -0.87) and left ventricular end-diastolic pressure (r = -0.74). There were modest correlations between both pressures and peak E/A, E wave deceleration time and A wave duration, respectively; r = 0.59, -0...Continue Reading

References

Jun 1, 1993·Journal of the American College of Cardiology·C P Appleton

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Citations

Apr 1, 2006·International Journal of Cardiology·Nearchos S NearchouAlexandros K Tsakiris
Jan 12, 2008·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Antonio VitarelliLidia Capotosto
Mar 27, 2007·International Journal of Cardiology·Stellan MörnerElsadig Kazzam
Feb 18, 2011·Journal of cardiology·Dae-Won Sohn
May 25, 2004·American Journal of Physiology. Heart and Circulatory Physiology·Soren SchenkKiyotaka Fukamachi
Jun 8, 1999·Current Opinion in Cardiology·S F Nagueh
May 25, 2021·The Canadian Journal of Cardiology·Dana ViskinYan Topilsky

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