Shortening ocular pain duration following intravitreal injections

European Journal of Ophthalmology
Lana Rifkin, Shlomit Schaal

Abstract

To determine ocular pain duration after routine in-office intravitreal injection and to determine whether topical eyedrops are beneficial in increasing patient comfort. Forty injection-naïve patients receiving routine intravitreal injections of bevacizumab for age-related macular degeneration were randomized into 3 groups: group 1 (control, no drops), group 2 (generic artificial tears), and group 3 (ketorolac tromethamine 0.4% eyedrops). Those who received topical medications were given a Visual Analog Pain score survey and asked to record their pain on a scale from 0 (no distress) to 10 (unbearable distress) daily until a score of 0 was achieved, at which point they were instructed to discontinue use of their given drops. Self-reported pain scores were assessed. Pain after routine intravitreal injection lasts on average between 3 and 7 days. Patients receiving topical ketorolac eyedrops reported the fewest average number of pain days (2.25±1.22) vs patients receiving artificial tears (3.54±1.13) or those who received no postprocedure eyedrops (5.13±1.25); p<0.05. At most, patients receiving ketorolac eyedrops reported 3 days of recordable pain. Those who received artificial tears reported at most 5 days of recordable pain, ...Continue Reading

References

Jan 1, 1992·Survey of Ophthalmology·A J Flach
Nov 9, 1974·Lancet·E C Huskisson
Jun 1, 1996·Journal of Cataract and Refractive Surgery·M K TuttonM G Fsadni
Sep 29, 2000·Cornea·S C PflugfelderM E Stern
Sep 21, 2005·Ophthalmology·Howesen KokSusan Lightman
Oct 6, 2006·The New England Journal of Medicine·Philip J RosenfeldUNKNOWN MARINA Study Group
Mar 16, 2007·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Andreas StahlNicolas Feltgen
Jul 9, 2009·Retina·Gholam A PeymanDarius M Moshfeghi
Nov 26, 2010·Retina·Gregory R BlahaJeffrey L Marx
Dec 15, 2010·American Journal of Ophthalmology·Eric D DonnenfeldRhett M Schiffman
Jan 26, 2011·Journal of Cataract and Refractive Surgery·Jared ParkerShahzad I Mian
May 7, 2011·The British Journal of Ophthalmology·Vip S GillDavid G Charteris

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Citations

Jan 15, 2020·Ophthalmic Surgery, Lasers & Imaging Retina·Joseph RaevisEric M Shrier
Nov 3, 2015·Acta Ophthalmologica·Paulina HaasSusanne Binder
May 18, 2018·Korean Journal of Ophthalmology : KJO·Seong Hwan ShinYong Kyu Kim
Jan 11, 2020·Survey of Ophthalmology·Shriji N PatelStephen J Kim
Sep 11, 2021·Ophthalmic Surgery, Lasers & Imaging Retina·Matthew S WiederJoyce N Mbekeani
Oct 30, 2020·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Mickael KarcentyOudy Semoun

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