Should Cervical Disc Arthroplasty Be Done on Patients with Increased Intramedullary Signal Intensity on Magnetic Resonance Imaging?

World Neurosurgery
Hsuan-Kan ChangHenrich Cheng

Abstract

Several trials from the U.S. Food and Drug Administration have demonstrated the success of cervical disc arthroplasty (CDA) in patients with degenerative disc disease causing radiculopathy, myelopathy, or both. For patients who had increased intramedullary signal intensity (IISI) on magnetic resonance image (MRI), however, the effectiveness and safety of CDA was unclear. This study aimed to evaluate the outcomes of CDA for patients with IISI on preoperative MRI. Consecutive patients who received 1-level CDA for symptomatic degenerative disc disease were reviewed retrospectively. Patients with IISI on preoperative T2-weighted MRI were compared to those without IISI (non-IISI). Clinical outcome parameters including visual analog scale, Neck Disability Index, Japanese Orthopedic Association (JOA), and Nurick scores were analyzed. Radiographic studies included dynamic lateral radiography and MRI. A total of 91 patients were analyzed (22 in the IISI group and 69 in the non-IISI group). The mean follow-up was 30.0 months. The demographic data were mostly similar between the 2 groups. All clinical outcomes, including visual analog scale, Neck Disability Index, JOA, and Nurick scores in the IISI group demonstrated significant improveme...Continue Reading

References

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Citations

Feb 2, 2017·Neurosurgical Focus·Hsuan-Kan ChangHenrich Cheng
May 11, 2019·Journal of Neurosurgery. Spine·Tsung-Hsi TuHenrich Cheng
Jul 11, 2020·Neurosurgery·Yi-Hsuan KuoWen-Cheng Huang
Dec 21, 2019·Journal of Neurosurgery. Spine·Atul Goel
Feb 1, 2020·Journal of Neurosurgery. Spine·Wen-Cheng HuangChao-Hung Kuo
Jan 4, 2020·Journal of Neurosurgery. Spine·Oliver Daniel MowforthBenjamin Marshall Davies

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